Introduction: Laryngeal plasmacytosis (LP) is a rare benign lesion of mature polyclonal plasma cells, which should be differentiated from extramedullary plasmacytoma.
Case Report: Isolated laryngeal plasmacytosis was discovered in a 59-year-old woman, free of symptoms other than chronic hoarseness.
Discussion: Histological presentation, treatment modalities and prognosis are discussed.
Conclusion: Laryngeal plasmacytosis is a rare benign lesion that must be considered in case of submucosal polyclonal plasma cell infiltrate.
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http://dx.doi.org/10.1016/j.anorl.2012.09.011 | DOI Listing |
Laryngoscope
January 2023
Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Mucous membrane plasmacytosis (MMP) is rare condition characterized by diffuse plasma cell infiltration of upper aero-digestive tract mucosa. It results in epithelial hyperplasia that has a classic papillary appearance. We describe a case of MMP primarily affect laryngeal and oropharyngeal mucosa resulting in progressive airway obstruction.
View Article and Find Full Text PDFLeuk Res Rep
November 2019
Department of Pathology, UMass Memorial Medical Center, Worcester, MA 01605, USA.
Mucous membrane plasmacytosis (MMP) is an uncommon variant of mucositis represented by a polyclonal plasma cell infiltration of mucosal tissue. Various clinical presentations in the upper airway have been reported ranging from erythematous mucosa to fungating masses. Histologic features include mucosal epithelial hyperplasia or psoriasiform changes with a dense submucosal infiltrate of polytypic plasma cells.
View Article and Find Full Text PDFAuris Nasus Larynx
April 2020
Department of Otolaryngology, Toho University School of Medicine, Tokyo, Japan.
Mikulicz's disease, an immunoglobulin G4-related disease (IgG4-RD) occurs frequently in the head and neck region but rarely in the larynx. We report a case of IgG4-RD with pseudotumor formation in the larynx. A 50-year-old man presented at our facility for a complete physical examination and diagnostic testing of a left arytenoid tumor.
View Article and Find Full Text PDFBr J Oral Maxillofac Surg
April 2015
Department of OMFS, Queen Victoria Hospital, Holtye Road, East Grinstead, West Sussex RH19 3DZ, United Kingdom. Electronic address:
Plasmacytosis of the mucous membrane is a rare, benign, inflammatory condition of poorly understood aetiology that affects the mucous membranes. Most reported cases involve the gingival tissues, larynx, and occasionally the lips. We describe an interesting case of orofacial plasmacytosis that affected the lower lip, mandibular gingiva, and buccal mucosa.
View Article and Find Full Text PDFEur Ann Otorhinolaryngol Head Neck Dis
November 2013
Service d'anatomie pathologique, faculté de médecine Paris Descartes Paris-5, hôpital européen Georges-Pompidou, 20-40, rue Leblanc, 75015 Paris, France.
Introduction: Laryngeal plasmacytosis (LP) is a rare benign lesion of mature polyclonal plasma cells, which should be differentiated from extramedullary plasmacytoma.
Case Report: Isolated laryngeal plasmacytosis was discovered in a 59-year-old woman, free of symptoms other than chronic hoarseness.
Discussion: Histological presentation, treatment modalities and prognosis are discussed.
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