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| http://dx.doi.org/10.4103/0976-7800.109648 | DOI Listing |
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Current trends in antimicrobial use and the role of antimicrobial stewardship in palliative oncology: a narrative review.
BMC Palliat Care
January 2025
Division of Infectious Diseases, Department of Internal Medicine, and Center for Infectious Diseases Research, American University of Beirut Medical Center, PO Box 11-0236, Riad , Beirut, 1107 2020, Lebanon.
Background: The overuse of antimicrobials is prevalent in palliative oncology care, with up to 86.9% of terminal cancer patients receiving these agents during end-of-life care. This overutilization stems from recurrent infections due to immunosuppression, malnutrition, and frequent hospitalizations, as well as difficulty differentiating infection-related symptoms from cancer-related complications.
View Article and Find Full Text PDFClinical features and temporal trends in H. pylori negative gastric maltoma.
Arab J Gastroenterol
January 2025
Division of Gastroenterology and Hepatology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:
Article Synopsis
- Mucosa-Associated Lymphoid Tissue (MALT) lymphoma, particularly gastric MALToma, is often associated with Helicobacter pylori (H. pylori) infection, though a significant number of cases occur without it.
- A study analyzed 52 patients with gastric MALToma from 2000 to 2021, finding that 48.1% were H. pylori-negative (HPN) and noted trends of increased HPN diagnoses in more recent years.
- Treatment outcomes showed that HPP patients had better responses to eradication therapy compared to HPN patients, who were more likely to receive additional chemo or radiotherapy.
- Despite these differences in treatment response, clinical features between HPP and HPN patients
Liver Cancer and Risk Factors in the MENA Region: Epidemiology and Temporal Trends Based on the 2019 Global Burden of Disease Data.
Cancer Control
November 2024
Faculty of Medicine, American University of Beirut Medical Center (AUBMC), Beirut, Lebanon.
Background: Liver cancer (LivCa) is a growing concern in the MENA region, driven by diverse factors, including viral hepatitis, lifestyle-related risks, and other causes.
Methods: Utilizing GBD 2019 data, we assessed LivCa patterns, emphasizing chronic viral hepatitis, non-viral factors, and health care disparities across the MENA region.
Results: Rising LivCa rates, particularly related to chronic viral hepatitis, highlight the region's health challenges.
From forgotten cure to modern medicine: The resurgence of bacteriophage therapy.
J Glob Antimicrob Resist
December 2024
Department of Experimental Pathology, Immunology and Microbiology, Faculty of Medicine, Center for Infectious Diseases Research, American University of Beirut, Beirut, Lebanon. Electronic address:
Objectives: The unregulated use of antibiotics has led to the rise of antibiotic-resistant bacterial strains. This study explores bacteriophage therapy as an alternative treatment, highlighting its history, significance, and advancements in Europe, the United States, and the Middle East.
Methods: A comprehensive literature review on bacteriophage therapy was conducted, focusing on its development, clinical trials, and patient treatment applications.
Stem cell transplantation in cerebrovascular accidents: A global bibliometric analysis (2000-2023).
World J Stem Cells
September 2024
INSERM U955-E01, Institut Mondor de Recherche Biomédicale, Université Paris-Est Créteil, Créteil 94000, France.
Background: Cerebrovascular accident (CVA) is a major global contributor to death and disability. As part of its medical management, researchers have recognized the importance of promising neuroprotective strategies, where stem cell transplantation (SCT) is thought to confer advantages trophic and neuroprotective effects.
Aim: To evaluate the current state of research on SCT in patients with CVA, assess key trends and highlight literature gaps.
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