Introduction: We compared the results of our computer simulation studies of Z-plasties of different design to those of earlier studies, such as laboratory studies in dogs.
Material And Methods: The contours of single Z-plasties of different designs on flat surfaces were transferred to finite element analytical software (ADINA version 8.7).
Results: The lengthening effect was almost proportional to the size of the Z-plasty, but was always less than what was predicted by geometric calculation. The percent gain in length decreased with the number of Z-plasties.
Conclusion: We used ADINA software analyze the lengthening effects of Z-plasties of different patterns. Our results support those of earlier experiments and should help increase our understanding of Z-plasties of various patterns.
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http://dx.doi.org/10.1272/jnms.80.218 | DOI Listing |
J Food Sci
January 2025
Department of Agricultural and Biological Engineering, University of Florida, Gainesville, Florida, USA.
Dry ice is one of the world's most in-demand commodities for cold-chain distribution of temperature-sensitive products. It offers an effective cooling solution without requiring mechanical refrigeration or specialized equipment. Dry ice is commonly produced as pellets and blocks.
View Article and Find Full Text PDFJMIR Res Protoc
January 2025
School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology, Nomi, Japan.
Background: The worldwide rise in the prevalence of noncommunicable diseases has increased the recognition of the need to identify modifiable risk factors for preventing and managing these diseases. The office worker, as a representative group of physically inactive workers, is exposed to risk factors for metabolic syndrome, which is a primary driver of noncommunicable diseases. The use of virtual reality (VR) exergames may offer a potential solution to the problem of increasing noncommunicable disease prevalence, as it can help individuals increase their physical activity levels while providing a more immersive experience.
View Article and Find Full Text PDFBrain Behav
January 2025
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Introduction: Patients with bipolar disorder (BD) demonstrate episodic memory deficits, which may be hippocampal-dependent and may be attenuated in lithium responders. Induced pluripotent stem cell-derived CA3 pyramidal cell-like neurons show significant hyperexcitability in lithium-responsive BD patients, while lithium nonresponders show marked variance in hyperexcitability. We hypothesize that this variable excitability will impair episodic memory recall, as assessed by cued retrieval (pattern completion) within a computational model of the hippocampal CA3.
View Article and Find Full Text PDFMol Divers
January 2025
School of Biological & Chemical Engineering, Zhejiang University of Science & Technology, Hangzhou, 310023, People's Republic of China.
The quinazoline scaffold serves as a fundamental framework, demonstrating potent anti-tumor activity. Employing the pharmacophore-based scaffold hopping principle, we successfully synthesized a series of FAK/PLK1 inhibitors incorporating the quinazoline scaffold. The synthesized compounds were characterized using H NMR, C NMR, and HRMS techniques.
View Article and Find Full Text PDFPlant Foods Hum Nutr
January 2025
Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Sea buckthorn is a model of medicine and food homology, but the chemical composition and mechanism of anti-inflammatory effects are limited. In this study, the key components and mechanisms of the anti-inflammatory effects of sea buckthorn were identified based on UPLC-Q-TOF-MS, network pharmacology, molecular docking, molecular dynamics and RAW264.7 cells.
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