Background: Differentiation between atrioventricular nodal reentry tachycardia (AVNRT) and atrioventricular reentrant tachycardia (AVRT) can be sometimes challenging. Apical right ventricular (RV) entrainment can help in differentiation; however, it has some fallacies. We thought to compare the accuracy of anteroseptal basal RV entrainment to RV apical entrainment in identifying the mechanism of supraventricular tachycardia (SVT).
Methods: Forty-two consecutive patients with SVT who underwent catheter ablation were prospectively studied. Apical RV entrainment was performed initially followed by basal entrainment from the anteroseptal basal RV avoiding His or atrial capture. Postpacing interval (PPI), PPI-tachycardia cycle length (TCL), corrected PPI-TCL, and stimulus-atrial minus ventricular-atrial (VA) intervals were measured.
Results: Entrainment was achieved from both sites of RV in 34 patients (ten men; mean age 42 ± 15 years), 20 with typical AVNRT, 1 with atypical AVNRT, and 13 with AVRT (eight left sided, four right sided, and one septal accessory pathways). PPI-TCL, corrected PPI (cPPI)-TCL, and stimulus-atrial-VA intervals were significantly longer with basal entrainment in AVNRT (171 ± 30 vs. 153 ± 22 ms (p = 0.003), 148 ± 21 vs. 131 ± 20 ms (p = 0.002), and 145 ± 17 vs. 136 ± 15 ms (p = 0.005), respectively). Receiver-operating characteristic curves showed higher AUC for the above parameters with basal entrainment compared to apical entrainment. Cutoff values of basal PPI-TCL of >110 ms and cPPI-TCL of >95 ms had better sensitivities (100 % for both vs. 95 and 90 %, respectively, for apical values) and specificities (85 and 92 % vs. 77 and 92 %, respectively) for diagnosis of AVNRT.
Conclusion: Basal RV entrainment from the anteroseptal basal RV is a simple maneuver that is superior to apical ventricular entrainment in identifying the mechanism of SVT.
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Front Neurol
January 2025
Department of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen, China.
Walking ability is essential for human survival and health. Its basic rhythm is mainly generated by the central pattern generator of the spinal cord. The rhythmic stimulation of music to the auditory center affects the cerebral cortex and other higher nerve centers, and acts on the central pattern generator.
View Article and Find Full Text PDFJ Neurosci
January 2025
Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, 40225 Germany
Recordings from Parkinson's disease (PD) patients typically show strong beta-band oscillations (13-35Hz), which can be modulated by deep brain stimulation (DBS). While high-frequency DBS (>100Hz) ameliorates motor symptoms and reduces beta activity in basal ganglia and motor cortex, the effects of low-frequency DBS (<30Hz) are less clear. Clarifying these effects is relevant for the debate about the role of beta oscillations in motor slowing, which might be causal or epiphenomenal.
View Article and Find Full Text PDFNeurobiol Dis
January 2025
Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taipei 10051, Taiwan. Electronic address:
Evidence indicates that neurodegenerative diseases spread through distinct brain networks. For Parkinson's disease (PD), somatosensory abnormalities may accompany motor dysfunction in early disease stages when dopaminergic degeneration is limited to the basal ganglia. It remains unclear whether, based on the network-spread account, these abnormalities emanated from aberrant functional connectivity with the basal ganglia, and whether interventions normalizing this connectivity could reverse these abnormalities.
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View Article and Find Full Text PDFBrain Sci
October 2024
Music and Health Science Research Collaboratory, University of Toronto, Toronto, ON M5S 1C5, Canada.
Background: Humans exhibit a remarkable ability to synchronize their actions with external auditory stimuli through a process called auditory-motor or rhythmic entrainment. Positive effects of rhythmic entrainment have been demonstrated in adults with neurological movement disorders, yet the neural substrates supporting the transformation of auditory input into timed rhythmic motor outputs are not fully understood. We aimed to systematically map and synthesize the research on the neural correlates of auditory-motor entrainment and synchronization.
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