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Pathological diagnosis and clinical feature analysis of descending duodenal mucosal adenocarcinoma: A case report.
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Department of Thoracic Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.
Background: Mucosal adenocarcinoma of the descending duodenum is a very rare gastrointestinal tumor. Due to its low incidence, it has rarely been the focus of clinical and pathological studies. The clinical manifestations of these tumors are usually nonspecific, and they are easily misdiagnosed or missed.
View Article and Find Full Text PDFEfficacy of Neoadjuvant Therapy for ROS1-Positive Locally-Advanced Lung Adenocarcinoma: A Case Report.
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Department of Thoracic Surgery, Linyi People's Hospital, Linyi, Shandong, China.
BACKGROUND ROS1 fusion-positive locally-advanced lung adenocarcinoma is a rare malignant tumor with no clear neoadjuvant therapy guidelines and a poor prognosis. This report describes a 49-year-old man with a ROS1 fusion-positive locally-advanced lung adenocarcinoma with a pathological complete response (pCR) to the tyrosine kinase inhibitor crizotinib combined with chemotherapy. CASE REPORT A 49-year-old Chinese man visited the hospital with a cough and phlegm that began over 20 days ago.
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Mature cystic teratoma (MCT) is the most common germ cell tumor of the ovary, comprising 20% of all ovarian neoplasms. Malignant transformation (MT) is an uncommon complication and occurs in approximately 1-3% of all MCTs. The most common histological type of MT is squamous cell carcinoma.
View Article and Find Full Text PDFDigital Papillary Adenocarcinoma: A Case Presentation and Literature Review.
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Digital papillary adenocarcinoma is a rare cutaneous tumor of eccrine origin that often presents as a papule or nodule on the dorsal aspect of a finger. It is challenging to diagnose because of its rarity, its benign appearance, and the lack of specific clinical or histological features. Excision is recommended, given the malignant nature and variable recurrence rates with metastases well documented in the literature.
View Article and Find Full Text PDFEntirely Exophytic HPV-associated Endocervical Adenocarcinoma: A Rare But Potentially Aggressive Neoplastic Phenomenon.
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Department of Laboratory Medicine and Pathobiology, University of Toronto.
A subset of human papillomavirus (HPV)-associated endocervical adenocarcinoma (EA) displays exclusively exophytic growth, with or without a classic villoglandular appearance. Given that increased depth and extent of destructive stromal invasion are associated with poorer prognosis for HPV-associated EA, it is believed that exclusively exophytic tumors are associated with a relatively indolent clinical course. There is, however, a paucity of data regarding the behavior of these neoplasms.
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