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Different phenotypes of hypertension and associated cardiovascular and all-cause mortality: a systematic review and meta-analysis.
Egypt Heart J
December 2024
Department of Internal Medicine, HIND Institute of Medical Sciences, Barabanki, India.
Background: Hypertension is a leading cause of premature mortality and morbidity. Recent guidelines advocate for out-of-office blood pressure monitoring, including ambulatory and home BP monitoring, to better identify hypertension phenotypes like masked hypertension, white coat hypertension, and sustained hypertension. However, clinical inertia persists due to a lack of robust evidence on the effectiveness of screening these phenotypes and their association with cardiovascular and all-cause mortality.
View Article and Find Full Text PDFGut microbiota-derived 4-hydroxyphenylacetic acid from resveratrol supplementation prevents obesity through SIRT1 signaling activation.
Gut Microbes
December 2025
Institute of Agri-Food Processing and Nutrition, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Resveratrol (RSV), a natural polyphenol, has been suggested to influence glucose and lipid metabolism. However, the underlying molecular mechanism of its action remains largely unknown due to its multiple biological targets and low bioavailability. In this study, we demonstrate that RSV supplementation ameliorates high-fat-diet (HFD)-induced gut microbiota dysbiosis, enhancing the abundance of anti-obesity bacterial strains such as and .
View Article and Find Full Text PDFLow rates of aortic surveillance imaging and clinical follow-up in patients with acute aortic dissection.
J Vasc Surg
December 2024
Division of Vascular and Endovascular Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.
Objectives: Patients that survive acute aortic dissection (AD) remain at high risk of morbidity/mortality from structural changes of the aorta. Aortic surveillance is challenging, especially within a tertiary referral center. Our aim was to identify follow-up imaging and appointment rates, and factors associated with incomplete surveillance in patients with acute AD.
View Article and Find Full Text PDFRace/ethnicity-specific association between the American Heart Association's new Life's Essential 8 and stroke in US adults with nonalcoholic fatty liver disease: Evidence from NHANES 2005-2018.
J Clin Neurosci
December 2024
Department of Neurosurgery, the First Affiliated Hospital of Shantou University Medical College, No.57 Changping Road, Shantou, Guangdong 515041, PR China. Electronic address:
Background: The Life's Essential 8 (LE8) is a recently introduced assessment of cardiovascular health (CVH) by the American Heart Association (AHA). Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease and is associated with an increased risk of stroke. We aimed to explore the association of LE8 with stroke in NAFLD using a national cross-sectional study.
View Article and Find Full Text PDFSimplifying coronary artery disease risk stratification: development and validation of a questionnaire-based alternative comparable to clinical risk tools.
EBioMedicine
December 2024
Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Background: Coronary artery disease (CAD) comprises one of the leading causes of morbidity and mortality both in the European population and globally. All established clinical risk stratification scores and models require blood lipids and physical measurements. The latest reports of the European Commission suggest that attracting health professionals to collect these data can be challenging, both from a logistic and cost perspective, which limits the usefulness of established models and makes them unsuitable for population-wide screening in resource-limited settings, i.
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