AI Article Synopsis

  • A 16-year-old male initially presented with blood in his urine but had normal ultrasound results and his symptoms resolved without follow-up.
  • After experiencing severe back pain and recurrent hematuria a month later, imaging revealed a large kidney tumor that had spread into the inferior vena cava.
  • Following surgery and chemotherapy for a diagnosis of primitive neuroectodermal tumor, the patient developed multiple lung metastases and ultimately passed away 18 months after diagnosis despite aggressive treatment.

Article Abstract

A 16-year-old man was referred to our hospital for asymptomatic gross hematuria. The findings of abdominal ultrasonography were normal. A month later, gross hematuria disappeared, and he was not followed after that. A month later, the patient was taken to our hospital in an ambulance for severe back pain and recurring gross hematuria. Computed tomography (CT) revealed a large right renal tumor with tumor thrombus penetrating inside the inferior vena cava. The patient underwent radical nephrectomy and embolectomy. The pathological diagnosis of the tumor was diagnosed as primitive neuroectodermal tumor (PNET) of kidney by immunostaining and gene analysis. We started adjuvant chemotherapy soon after the operation. However, at 10 months after, multiple pulmonary metastases were detected. The patient was treated with salvage chemotherapy, surgery and irradiation therapy as combined modality therapy. Nevertheless, he died 18 months after the diagnosis.

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