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A Couple-Based Intervention for Chinese Older Adults With Type 2 Diabetes: A Randomized Clinical Trial.
JAMA Netw Open
January 2025
Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Importance: Spousal involvement in diabetes care is recommended theoretically, but effectiveness in clinical settings and among diverse populations is unclear.
Objective: To test the effect of a couple-based intervention among Chinese older patients with type 2 diabetes and their spouses.
Design, Setting, And Participants: This multicenter randomized clinical trial comprised 2 arms: a couple-based intervention arm and an individual-based control.
The SwiftScan step-and-shoot continuous mode improves SPECT scanning efficiency: a preliminary phantom and clinical test.
EJNMMI Phys
January 2025
Department of Nuclear Medicine, Lanzhou University Second Hospital, Lanzhou, 730030, China.
Purpose: The aim of the study was to investigate the value of SwiftScan Step-and-Shoot Continuous (SSC) scanning mode in enhancing image quality and to explore appropriate scanning parameters for reducing scan time.
Methods: This study was composed of a phantom study and two clinical tests. The differences in visual image quality scores, coefficient of variance (COV) of the background, image signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and recovery coefficient (RC) of the sphere were compared between SSC mode and traditional Step-and-Shoot (SS) mode in the phantom study.
Women's preferences regarding the use of chaperones during proctological examinations conducted by male physicians: a randomised clinical trial.
Int J Colorectal Dis
January 2025
Department of Surgery, Division of Coloproctology, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande Do Sul. Room 600 A, Rua Ramiro Barcelos, Porto Alegre, RS, 2350, Brazil.
Purpose: The presence of chaperones during intimate physical examinations is a matter of ongoing debate. While most guidelines recommend the use of chaperones in all cases, there are no clinical trials specifically investigating intimate exams performed on women by male physicians. We aimed to evaluate female patients' perceptions regarding the presence or absence of chaperones during proctological examinations conducted by male physicians.
View Article and Find Full Text PDFDPYD genotype should be extended to rare variants: report on two cases of phenotype / genotype discrepancy.
Cancer Chemother Pharmacol
January 2025
Service de Génomique des Tumeurs et Pharmacologie, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris, Paris, France.
The enzyme dihydropyrimidine dehydrogenase (DPD) is the primary catabolic pathway of fluoropyrimidines including 5 fluorouracil (5FU) and capecitabine. Cases of lethal toxicity have been reported in cancer patients with complete DPD deficiency receiving standard dose of 5FU or capecitabine. DPD is encoded by the pharmacogene DPYD in which more than 200 variants have been identified.
View Article and Find Full Text PDFFertility preservation options at cancer diagnosis; classifying use and decision-making in the United States.
Expert Rev Endocrinol Metab
January 2025
Department of OBGYN, Grossman School of Medicine, New York University, NY, USA.
Introduction: Incidence rates for cancer among adolescent and young adults (AYA) have increased 30% since 1970. Declines in mortality underscore the importance of discussing fertility preservation (FP) options prior to receiving gonadotoxic treatments. National guidelines outline FP options including oocyte (OC), embryo (EC), and ovarian tissue cryopreservation (OTC) for female AYA patients.
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