A parathyroid lipoadenoma is a very rare cause of mediastinal mass. The clinical features of this pathologic entity is similar to those of the more common pathologic variants of parathyroid disease associated with primary hyperparathyroidism. A 58-year-old woman presented with huge multinodular goiter. Her thoracic CT scan was done before surgery, showed a posterior mediastinal mass. On microscopic examination, the thyroid was composed of thyroid follicles in varies sizes, compatible with a multinodular goiter and the mediastinal mass, microscopically, was composed of epithelial cells arranged in follicular and cellular nests pattern alter with abundant mature adipose tissue, morphologically closely resembled parathyroid tissue. Thyroid, mesenchymal and neuroendocrine origin for this tumor excluded by immunohistochemistry and the mass was diagnosed as a parathyroid lipoadenoma. In our case, there is a non functional parathyroid lipoadenoma with a very rare presence.
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J Med Ultrason (2001)
December 2024
Department of Internal Medicine, Kuma Hospital, Kobe, Hyogo, 650-0011, Japan.
Purpose: Parathyroid lipoadenomas are difficult to recognize preoperatively; hence, they may remain undetected. Difficulty in recognition is thought to be due to the adipocytes present in the tumor. This study aimed to clarify the impact of adipocytes as a component of parathyroid adenomas on ultrasound evaluation.
View Article and Find Full Text PDFInt J Surg Case Rep
August 2024
Department of Surgery, Galway University Hospitals, Republic of Ireland.
Introduction: Parathyroid lipoadenomas are a rare parathyroid phenomenon and an unusual cause of primary hyperparathyroidism. A difficult diagnosis to make, there are less than 100 cases in the literature since they were first described in 1958, and to our knowledge this is the largest parathyroid lipoadenoma to be reported.
Presentation Of Case: A minimally-invasive parathyroidectomy with intraoperative parathyroid hormone monitoring was performed in the case of a male with a large neck mass and symptomatic primary hyperparathyroidism.
The diagnosis of pathological conditions of the parathyroid glands is the answer to clinically more frequently detected hypercalcemic conditions, including MEN syndromes. In routine biopsy practice, enlarged bodies are also a differential diagnosis for the diagnosis of thyroid nodules. In the chapter of parathyroid tumors, the 5th edition of the WHO classification brings changes influenced similarly to other endocrine organs by the increase in genetic information.
View Article and Find Full Text PDFClin Case Rep
December 2023
Division of Thyroid Surgery China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma Changchun China.
Parathyroid lipoadenoma is a rare type of parathyroid adenoma, described as a single parathyroid adenoma with more than 50% fat on histologic examination and an unknown etiology, which is one of the rare causes of primary hyperparathyroidism. The difficulty of parathyroid lipoadenoma is mainly diagnosed by preoperative imaging localization. We hope to arouse attention to the parathyroid adenoma which is difficult to locate through our case report.
View Article and Find Full Text PDFJ Clin Lipidol
March 2024
Ege University Faculty of Medicine (Dr Gunsar), Department of Gastroenterology, Izmir, Turkey.
Chanarin-Dorfman Syndrome (CDS) is a rare lipid storage disease with ichthyosis, hepatomegaly, myopathy, neuropathy, deafness, and ocular findings. Here, we aim to present an elderly CDS case and highlight the new endocrinological findings. A 66-year-old male patient with cirrhosis was hospitalized for liver transplantation.
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