PharmGKB: the Pharmacogenomics Knowledge Base.

Methods Mol Biol

Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA.

Published: February 2014

AI Article Synopsis

  • PharmGKB is an online tool that helps researchers understand how genetic differences influence how people respond to drugs.
  • The website offers integrated information on genes, molecular data, and clinical details, allowing users to explore connections between genetics and drug response.
  • Access is free for registered users who agree to use the data only for research and not for redistribution, enabling them to download valuable information for future studies.

Article Abstract

The Pharmacogenomics Knowledge Base, PharmGKB, is an interactive tool for researchers investigating how genetic variation affects drug response. The PharmGKB Web site, http://www.pharmgkb.org , displays genotype, molecular, and clinical knowledge integrated into pathway representations and Very Important Pharmacogene (VIP) summaries with links to additional external resources. Users can search and browse the knowledgebase by genes, variants, drugs, diseases, and pathways. Registration is free to the entire research community, but subject to agreement to use for research purposes only and not to redistribute. Registered users can access and download data to aid in the design of future pharmacogenetics and pharmacogenomics studies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084821PMC
http://dx.doi.org/10.1007/978-1-62703-435-7_20DOI Listing

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