The clinical practice of endodontic therapy is relatively common, especially in the anterior of the mouth, with easy access to cavities and in cases of mechanical debridement. However, problems such as perforation of the root canal can occur during treatment, and can cause periodontal tissue damage and esthetic problems. The treatment of root canal perforation consists of periodontal and endodontic therapy, as well as selecting the best material for perforation repair. This is a case report of iatrogenic root perforation on an anterior tooth that required combined restorative, periodontal, surgical, and endodontic approaches. The case describes the use of a subepithelial connective tissue graft (SCTG) on a resin ionomer-restored root surface for the treatment of root perforation and periodontal damage caused by an iatrogenic procedure, with a 12-month follow-up. This case report shows that SCTG can successfully treat root perforations associated with a resin ionomer-restored root surface.

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