New cycloartane triterpene glycosides from Beesia calthaefolia.

Nat Prod Res

a Department of Clinical Pharmacology , General Hospital of People's Liberation Army, Beijing , 100853 , China.

Published: July 2014

Two new cycloartane triterpene glycosides (compounds 1 and 4) were isolated from the whole plants of Beesia calthaefolia with two known glycosides (compounds 2 and 3). Compounds 1 and 4 were assigned as (20S(*),24R(*))-16β-acetoxy-20, 24-epoxy-9, 19-cyclolanostane-3β,12β,15α,18,25-pentaol-3-O-β-d-xylopyranoside and (20S(*),24 R(*))-16β-acetoxy-20,24-epoxy-9,19-cyclolanostane-3β,15α,18,25-tetraol-3-O-β-d-xylopyranoside, respectively. Their structures were elucidated on the basis of extensive spectroscopic data analyses and comparison with spectroscopic data reported. Compounds 1 and 4 showed potential inhibition activity for the proliferation of splenocytes.

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http://dx.doi.org/10.1080/14786419.2013.811407DOI Listing

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