Lichen nitidus (LN) is a rare skin disorder presenting with multiple, small and bright papules located on the chest, abdomen, penis glans and upper extremities. It usually presents with limited involvement; however, it can present as generalized involvement. There is no consensus on treatment. Corticosteroid, astemizole, phototherapy has been used; however, the results are controversial. A 15-year-old male with clinical and histopathological diagnosis of LN was treated with narrow-band ultraviolet B (NB-UVB). The lesions completely regressed with post-inflammatory hypopigmentation on the second month of the therapy (25 sessions). We believe that NB-UVB is an effective treatment on generalized LN.
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Article Synopsis
- Perforating lichen nitidus is a rare skin condition, with only about 11 cases documented globally, usually affecting young males in areas that experience frequent mechanical irritation like hands and elbows.
- The condition features distinct histopathological characteristics, including a specific lymphohistiocytic inflammation within the skin layers, leading to the elimination of dermal materials through the skin surface.
- This case study is notable as it describes the first instance of perforating lichen nitidus in a patient with atopic dermatitis undergoing dupilumab treatment, indicating that while atopic dermatitis improved, the lichen nitidus worsened, hinting at a unique underlying mechanism for the condition.
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