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The epidemiology of infection is changing. CDI, usually depicted as a nosocomial infection in the elderly, is now occurring in community-dwelling persons who are younger and otherwise dissimilar. A more virulent isolate (North American Pulsed Field type (NAP) associated with increased morbidity and mortality, has been identified. In 2005, similar strains were associated with severe disease in community-dwelling patients at a rate of 7.6/100,000. Screening patients with potential CDI symptoms and implementing preventative measures, including judicious use of antibiotics, can reduce disease burden.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694783 | PMC |
| http://dx.doi.org/10.1016/j.nurpra.2012.10.007 | DOI Listing |
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