AI Article Synopsis
- Myopathy is frequently observed in hypothyroidism, but extremely high creatinine kinase (CK) levels are uncommon.
- Hypothyroidism can lead to increased creatinine due to reduced glomerular filtration rate, though elevated production is rare.
- A case is presented where severe hypothyroidism resulted in significantly high CK and creatinine levels, both of which decreased with treatment.
Article Abstract
Myopathy is common in hypothyroidism, but a very high creatinine kinase (CK) level in the range commonly seen with inflammatory myopathy is rare. Reversible elevation of creatinine is known to occur in hypothyroidism due to a decrease in the glomerular filtration rate, but it can also occur rarely due to enhanced creatinine production. We present a case of severe hypothyroidism with massively elevated CK levels and high creatinine levels, both of which reversed on treatment of hypothyroidism.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692151 | PMC |
| http://dx.doi.org/10.4103/0971-4065.111859 | DOI Listing |
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