Mycotic cerebral aneurysm is a rare and potentially fatal complication of infective endocarditis. A young man was diagnosed with culture negative infective endocarditis of mitral valve with cerebral aneurysm. The patient was started on conservative management, but he died owing to intracerebral haemorrhage. In the absence of large randomised trials, there is a lack of consensus regarding the management of unruptured aneurysms. Since mycotic aneurysms are known to resolve or decrease in size with antimicrobial therapy, several institutions advice the conservative approach. A few case reports like the present case have shown that the risk of aneurysmal rupture and death is considerably high with the conservative approach. Endovascular therapy has shown to reduce the mortality in this subgroup. These patients should be managed aggressively with endovascular or surgical procedure along with antimicrobial therapy.
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http://dx.doi.org/10.1136/bcr-2013-200016 | DOI Listing |
Eur Heart J
January 2025
Department of Cardiovascular Medicine, Tohoku University Hospital, Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
J Am Heart Assoc
January 2025
Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine Mayo Clinic College of Medicine and Science Rochester MN USA.
Background: Echocardiographic evaluation of vegetations is crucial in infective endocarditis (IE). Although several studies have noted a link between larger vegetations and an increased risk of embolization, a more comprehensive evaluation of vegetation characteristics in a contemporary cohort has not been conducted. Our study aimed to define the short-term risk of symptomatic embolization in patients with IE.
View Article and Find Full Text PDFHosp Pharm
January 2025
Division of General Internal Medicine, Department of Medicine, Center for Research in Healthcare, University of Pittsburgh, Pittsburgh PA, USA.
We describe a case of a 67-year-old man with bioprosthetic aortic valve endocarditis secondary to , a rare Gram-negative plant pathogen. The initial source was assumed to be due to soil exposure. The patient was successfully managed with ceftriaxone following aortic valve replacement.
View Article and Find Full Text PDFOpen Forum Infect Dis
January 2025
Division of Public Health, Infectious Disease, and Occupational Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
The skip phenomenon (SP) is a pattern where blood cultures are intermittently positive before final clearance. We report that one-third of patients with infective endocarditis experienced the SP. Patients with the SP experienced both a longer duration of bacteremia and hospital stay, with a higher 1-year mortality rate.
View Article and Find Full Text PDFBMC Neurol
January 2025
Department of Neurology, LMU University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
Background: Purulent meningitis poses a significant clinical challenge with high mortality. We present the case of a 54-year-old female transferred to our emergency department with suspected bacterial meningitis, later diagnosed as an Austrian syndrome.
Case Presentation: The patient exhibited subacute somnolence, severe headache, nausea and fever.
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