AI Article Synopsis
Article Abstract
Background: Acute thallium poisoning rarely occurs but is a serious and even fatal medical condition. Currently, patients with acute thallium poisoning are usually treated with Prussian blue and blood purification therapy. However, there are few studies about these treatments for acute thallium poisoning.
Methods: Nine patients with acute thallium poisoning from 1 family were treated successfully with Prussian blue and different types of blood purification therapies and analyzed.
Results: Prussian blue combined with sequential hemodialysis, hemoperfusion and/or continuous veno-venous hemofiltration were effective for the treatment of patients with acute thallium poisoning, even after delayed diagnosis.
Conclusions: Blood purification therapies help in the clearance of thallium in those with acute thallium poisoning. Prussian blue treatment may do the benefit during this process.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/MAJ.0b013e318298de9c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Thallium reabsorption via NKCC2 causes severe acute kidney injury with outer medulla-specific calcium crystal casts in rats.
Arch Toxicol
December 2024
Department of Nephrology and Hypertension, Dokkyo Medical University, Tochigi, Japan.
Article Synopsis
- Thallium (Tl) is a highly toxic heavy metal linked to accidental poisoning and can cause severe health issues including kidney failure.
- In a study on rats, intraperitoneal administration of Tl led to significant kidney dysfunction, characterized by high calcium deposits and mitochondrial issues in a specific kidney region called the medullary thick ascending limb (mTAL).
- The research found that inhibiting a specific kidney transporter helped reduce Tl accumulation and its damaging effects, which could lead to new treatment strategies for Tl poisoning and improve diagnostic methods for related kidney damage.
Potential Effects of Ischemic Postconditioning and Changes in Heat Shock Protein 72 in Patients with Acute Myocardial Infarction without Prodromal Angina.
Int Heart J
May 2024
Division of Cardiology, Department of Internal Medicine, Asahikawa Medical University.
The effectiveness of ischemic postconditioning (iPoC) in patients with ST-elevation myocardial infarction (STEMI) without ischemic preconditioning has not been determined. Therefore, we investigated the impact of iPoC and its potential mechanism related to heat shock protein 72 (HSP72) induction on myocardial salvage in patients with STEMI without prodromal angina (PA).We retrospectively analyzed data from 102 patients with STEMI with successful reperfusion among 323 consecutive patients with acute coronary syndrome.
View Article and Find Full Text PDFThallium - poisoner's poison: An overview and review of current knowledge on the toxicological effects and mechanisms.
Curr Res Toxicol
February 2024
Shimane Institute for Industrial Technology, 1 Hokuryo, Matsue, Shimane 690-0816, Japan.
Thallium (Tl) is one of the most toxic metals and its historic use in homicides has led it to be known as "the poisoner's poison." This review summarizes the methods for identifying Tl and determining its concentrations in biological samples in recently reported poisoning cases, as well as the toxicokinetics, toxicological effects, toxicity mechanisms, and detoxication methods of Tl. Recent findings regarding Tl neurotoxicological pathways and toxicological effects of Tl during pregnancy are also presented.
View Article and Find Full Text PDFPainful Sensory Motor Neuropathy With Albuminocytological Dissociation of the Cerebrospinal Fluid as the Presenting Features of Acute Thallium Poisoning.
J Clin Neurol
November 2023
Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!