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Emerging Research and Future Directions on Doxorubicin: A Snapshot.
Asian Pac J Cancer Prev
January 2025
All India Institute of Medical Sciences, Department of Biochemistry, Vijaypur, Jammu, India.
Doxorubicin, a widely used anthracycline antibiotic, has been a cornerstone in cancer chemotherapy since the 1960s. In addition to doxorubicin, anthracycline chemotherapy medications include daunorubicin, idarubicin, and epirubicin. For many years, doxorubicin has been the chemotherapy drug of choice for treating a broad variety of cancers.
View Article and Find Full Text PDFThe Value and Importance of a Professional Ethical Code for Medicines Development: IFAPP International Ethics Framework.
Pharmaceut Med
January 2025
Pharmaceutical Medicine, Dover Heights, Sydney, NSW, Australia.
Pharmaceutical medicine professionals have to face many ethical problems during the entire life span of new medicines extending from animal studies to broad clinical practice. The primary aim of the general ethical principles governing research conducted in humans is to diminish the physical and psychological burdens of the participants in human drug studies but overlooks many additional social and ethical problems faced by medicine developers. These arise mainly at the interface connecting the profit-oriented pharmaceutical industry and the healthcare-centered medical profession cooperating in medicines development.
View Article and Find Full Text PDFEvaluating C-Reactive Protein and Procalcitonin Discordance Among Febrile Infants at Risk of Serious Bacterial Infections.
Acta Paediatr
January 2025
Department of Emergency Medicine, KK Women's and Children's Hospital, SingHealth-Duke NUS Paediatrics Academic Clinical Programme, Duke-NUS Medical School, Singapore.
Aim: We aimed to investigate the prevalence and factors associated with C-reactive protein (CRP) and procalcitonin (PCT) discordance in febrile infants with serious bacterial infections (SBIs).
Methods: We performed a retrospective review of febrile infants ≤ 90 days old presenting to the emergency department between December 2018 and June 2023. We compared conservative and pragmatic thresholds for PCT (< 0.
Quercetin, a natural flavonoid induced by the spider mite Tetranychus urticae or alamethicin, is involved in the defense of lima bean against spider mites.
Pest Manag Sci
January 2025
College of Plant Protection, Yangzhou University, Yangzhou, China.
Background: Phaseolus lunatus, commonly known as the lima bean, is a leguminous crop cultivated in various regions worldwide. It is native to tropical America and is extensively grown in both tropical and temperate climates. Lima beans are highly nutritious and versatile, serving not only as a food and vegetable, but also as a source of green manure.
View Article and Find Full Text PDFRisk factors for inferior alveolar nerve injury associated with implant surgery: An observational study.
J Dent Sci
January 2025
Department of Oral and Maxillofacial Surgery, Seoul National University Dental Hospital, Seoul, Republic of Korea.
Background/purpose: Inferior alveolar nerve (IAN) injury is the most serious complication associated with dental implant surgery, posing difficulties in treatment and potential for permanent disabilities. This study aimed to identify patient-related risk factors for IAN injury during implant placement and to investigate sensory disturbances depending on whether the implant was removed.
Materials And Methods: Twenty-eight patients with implant-related IAN injury were included.
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