AI Article Synopsis
- No reflow is a significant complication after primary percutaneous coronary intervention (PCI) in treating heart attacks, with some cases being reversible (transient) and others not (persistent).
- The study involved 123 patients with no reflow, comparing those with transient (59 patients) and persistent (64 patients) no reflow to identify clinical features and outcomes.
- Findings revealed that those with transient no reflow had a lower in-hospital cardiac death rate and potential predictors for recovery include good initial blood flow (TIMI grade 3) and better kidney function (as indicated by glomerular filtration rate).
Article Abstract
No reflow following primary percutaneous coronary intervention (PCI) is a serious complication in the treatment of acute myocardial infarction. No reflow in some patients is reversible (transient no reflow), whereas no reflow in others persists until the end of the procedure (persistent no reflow). The aim of this study was to identify clinical features of transient no reflow following primary PCI. Consecutive patients with no reflow (n = 123) were enrolled following primary PCI. Among them, 59 patients were in the transient group and 64 in the persistent group. We compared clinical features and hospital outcomes between the two groups. Multivariate logistic regression analysis was performed to identify the determinants of transient no reflow. The transient group had a lower rate of in-hospital cardiac death than the persistent group (0 vs. 6.4 %, relatively, P = 0.018). There was a trend for a shorter length of hospital stay in the transient group. Multivariate logistic regression analysis identified initial thrombolysis in myocardial infarction (TIMI) flow grade 3 (OR 6.239, 95 % CI 1.727-22.541, P = 0.005) and a higher estimated glomerular filtration rate (OR 1.204, 95 % CI 1.006-1.440, P = 0.042) as independent predictors of transient no reflow. Transient no reflow tended to be associated with TIMI thrombus grade ≤3 (OR 2.879, 95 % CI 0.928-8.931, P = 0.067). In conclusion, initial TIMI flow grade 3 and preserved renal function were associated with recovery from no reflow. Initial angiographic finding such as TIMI flow or TIMI thrombus grade might be an important predictor of recovery from the no-reflow phenomenon.
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| http://dx.doi.org/10.1007/s00380-013-0379-1 | DOI Listing |
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