AI Article Synopsis
- A case was reported of an 82-day-old infant who developed acute immune thrombocytopenic purpura (ITP) after receiving the second dose of the oral polio vaccine (OPV).
- The infant, previously healthy and not on any medications, had a very low platelet count of 13×10(9)/L, with elevated platelet-associated IgG suggesting an immune response.
- After proper treatment, the infant recovered within 30 days, highlighting the need for awareness of potential thrombocytopenia linked to OPV, although it occurs less frequently compared to natural infections.
Article Abstract
A case of acute immune thrombocytopenic purpura following oral polio vaccine (OPV) is reported. An 82-d-old infant developed purpura at the same day after the second dose of oral polio vaccine. Until the time of hospital admission, the male infant had been in good health and had not received any drugs, and the possible causes of this condition were excluded. His platelet count was 13×10(9)/L. Platelet-associated IgG was elevated, but the amount of megakaryocytes in bone marrow aspirates was within the normal range, suggesting immune mechanism-associated thrombocytopenia. The infant recovered with the proper treatment within 30 d. Attention should be paid to OPV-associated thrombocytopenia, though it seems to be less frequent than after natural infections.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906275 | PMC |
| http://dx.doi.org/10.4161/hv.24847 | DOI Listing |
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