AI Article Synopsis

  • The treatment of acute marrow failure caused by radiation primarily involves supportive, replacement, and stimulating therapies.
  • The text discusses modern methods for preventing and treating infections, along with the benefits and limitations of transfusions from donor sources like platelets and plasma.
  • The analysis highlights the potential of therapies such as bone marrow transplantation and cytokine-based treatments like interleukin and thrombopoietin in improving outcomes for patients with acute radiation syndrome.

Article Abstract

It is shown, that tactics of treatment of acute marrow failure of radiant etiology is based, first of all, on measures of supporting, replaceable and stimulating therapy. The modern means, used for prophylactic and treatment of infectious complications, are resulted. Opportunities and restrictions of transfusion of donor thrombocytes and granulocytes, erythrocytes and chilled plasma are described. Therapeutic efficiency of transplantation of a bone marrow, cells of embryonic liver and stem cells of peripheral or umbilical cord blood is analyzed. It is shown, that the greatest prospects in perfection of the specialized medical aid at acute radiation syndrome are connected to complex application of interleukin-1beta, interleukin-3, granulocyte or granulocyte/macrophage colony stimulated factor, thrombopoietin and others cytokines.

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