Two plasmid variants of the main subspecies of the plague microbe circulate in a Central Caucasian high-altitude natural focus of plague. The strains of one plasmid variant fully correspond to the main subspecies of the plague pathogen in their characteristics. Those of the other are auxotrophic for proline, weakly virulent to one or both species of laboratory animals. The mountain subspecies of Citellophilus tesquorum fleas excretes the greatest quantity of plague microbe strains so the investigation of whether unblocked fleas can transmit the plague microbe is of interest.

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