During cochlear implantation, hearing preservation is a concern. Minimizing disturbances to the cochlea and protection of the underlying endosteal membrane during the formation of a cochleostomy are considered important factors. The robotic micro-drill system tested in this article is the first example of an autonomous surgical drill successfully producing a cochleostomy, which keeps the underlying endosteal membrane intact. This study compares induced disturbances within the cochlea during formation of cochleostomy using the robotic micro-drill with that of conventional manual drilling. The disturbance of the endosteal membrane is measured using a Microscope Scanning Vibrometer at a third window, produced in the cochlea. Results show that the highest velocity amplitude measured was associated with manual drilling technique. The robotic micro-drill technique produced only about 1% of the peak velocity amplitude seen in manual drilling and exhibited much more uniform behaviour, while keeping the underlying membrane intact. The technique applied when using the robotic drill could be a major step in reducing the trauma to the cochlea, by reducing disturbance levels.
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http://dx.doi.org/10.1177/0954411913488507 | DOI Listing |
J Prosthodont
October 2023
Department of Oral Implantology, Tianjin Stomatological Hospital, Tianjin Stomatological Hospital, School of Medicine, Nankai University & Tianjin Key Laboratory of Oral and Maxillofacial Function Reconstruction, Tianjin, China.
The unique anatomical structure of the atrophic edentulous maxilla limits the placement of endosteal root form dental implants without bone grafting and augmentation. Surgical placement of zygomatic implants in an optimal position remains challenging. This technique report illustrates a novel digital guide technology, including the design workflow, application method, and indications for assisting with the placement of zygomatic implants using a bone-supported titanium double-sleeve guide.
View Article and Find Full Text PDFWorld Neurosurg
July 2023
Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, Louisiana, USA; Department of Structural & Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, USA; Departmentof Anatomical Sciences, St. George's University, St. George's, West Indies, Grenada; Department of Neurosurgery and Ochsner Neuroscience Institute, Ochsner Health System, New Orleans, Louisiana, USA.
Background: Published reports regarding the tissue types that surround the internal carotid artery (ICA) as it travels through the carotid canal vary. Reports have variably defined this membrane as periosteum, loose areolar tissue, or dura mater. With such discrepancies and realizing that knowledge of this tissue might be important for skull base surgeons who expose or mobilize the ICA at this location, the present anatomical/histological study was performed.
View Article and Find Full Text PDFFront Oncol
October 2022
Blood and Cancer Biology Laboratory, Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.
Intracellular calcium signaling regulates diverse physiological and pathological processes. In solid tumors, changes to calcium channels and effectors mutations or changes in expression affect all cancer hallmarks. Such changes often disrupt transport of calcium ions (Ca) in the endoplasmic reticulum (ER) or mitochondria, impacting apoptosis.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
August 2022
Department of Otorhinolaryngology and Head & Neck Surgery, R.L Jalappa Hospital, Kolar, Karnataka India.
This study has aimed to determine the anatomical site of labyrinthine fistula in patients of chronic suppurative otitis media at our centre. Labyrinthine fistulae (LF) are caused by abnormal communications between the inner ear and surrounding structures resulting in perilymph leakage and hearing loss. Labyrinthine fistula represents as erosive loss of the enchondral bone overlying the semicircular canals without loss of perilymph.
View Article and Find Full Text PDFBiomater Transl
December 2020
Department of Biomedical Engineering, School of Materials Science and Engineering, South China University of Technology, Guangzhou, Guangdong Province, China.
Alveolar ridge atrophy brings great challenges for endosteal implantation due to the lack of adequate vertical bone mass to hold the implants. To overcome this limitation, we developed a novel dental implant design: sub-scaffold dental implant system (SDIS), which is composed of a metal implant and a micro-nano bioactive glass scaffold. This implant system can be directly implanted under mucous membranes without adding any biomolecules or destroying the alveolar ridge.
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