Population-based incidence of invasive haemophilus influenzae and pneumococcal diseases before the introduction of vaccines in Japan.

Pediatr Infect Dis J

From the *Okinawa University, Institute for Regional Studies, Okinawa; and †Sapporo City University, School of Nursing, Sapporo, Japan.

Published: December 2013

AI Article Synopsis

  • Before vaccines were introduced, bacterial meningitis rates in children (28 days to 5 years) in Hokkaido, Japan, were 8.48 cases per 100,000 person-years.
  • Haemophilus influenzae type-b accounted for 5.65 cases and Streptococcus pneumoniae for 1.85 cases per 100,000 person-years.
  • Additionally, the incidence of bacteremia was significantly higher, with S. pneumoniae causing 60.15 cases and H. influenzae causing 18.80 cases per 100,000 person-years.

Article Abstract

Before the introduction of vaccines, the incidence of bacterial meningitis among children aged 28 days to 5 years was 8.48, Haemophilus influenzae type-b meningitis was 5.65 and Streptococcus pneumoniae meningitis was 1.85 per 100,000 person-years in Hokkaido, Japan. The incidence of bacteremia caused by S. pneumoniae was 60.15 and H. influenzae was 18.80.

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http://dx.doi.org/10.1097/INF.0b013e3182a14971DOI Listing

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