Enantiopure hemicryptophanes efficiently discriminate chiral ammonium neurotransmitters. The ephedrine and norephedrine molecules associate with hemicryptophane hosts to form 1:1 and 1:2 host-guest complexes. Binding constants are determined by fitting the ¹H nuclear magnetic resonance (NMR) titration curves to give β₁ and β₂ values, which are used to characterize the diastereomeric and enantiomeric discriminating potentials of the hosts.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/chir.22195 | DOI Listing |
Publication Analysis
Top Keywords
ammonium neurotransmitters
8
hemicryptophane hosts
8
chiral discrimination
4
discrimination ammonium
4
neurotransmitters c₃-symmetric
4
c₃-symmetric enantiopure
4
enantiopure hemicryptophane
4
hosts enantiopure
4
enantiopure hemicryptophanes
4
hemicryptophanes efficiently
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!