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Rapid optical determination of salivary cortisol responses in individuals undergoing physiological and psychological stress.
Sci Rep
December 2024
Research Centre for Biomedical Engineering (RCBE), School of Science and Technology, City, University of London, Northampton Square, London, EC1V 0HB, UK.
Traditional methods for management of mental illnesses in the post-pandemic setting can be inaccessible for many individuals due to a multitude of reasons, including financial stresses and anxieties surrounding face-to-face interventions. The use of a point-of-care tool for self-management of stress levels and mental health status is the natural trajectory towards creating solutions for one of the primary contributors to the global burden of disease. Notably, cortisol is the main stress hormone and a key logical indicator of hypothalamic-pituitary adrenal (HPA) axis activity that governs the activation of the human stress system.
View Article and Find Full Text PDFTrivalent recombinant protein vaccine induces cross-neutralization against XBB lineage and JN.1 subvariants: preclinical and phase 1 clinical trials.
Nat Commun
December 2024
Laboratory of Aging Research and Cancer Drug Target, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.
The immune escape capacities of XBB variants necessitate the authorization of vaccines with these antigens. In this study, we produce three recombinant trimeric proteins from the RBD sequences of Delta, BA.5, and XBB.
View Article and Find Full Text PDFCost Outcomes of Virtual Surgical Planning in Head and Neck Reconstruction: A Systematic Review.
Head Neck
December 2024
Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Background: Virtual surgical planning (VSP) is an emerging method in head and neck reconstruction with demonstrated benefits, however, its economic viability is supported with mixed evidence.
Methods: A structured search was performed in five electronic databases. Studies that performed an economic evaluation on VSP in head and neck reconstruction were included.
Validity and Reliability of the Videoconference-Based Berg Balance Scale in Stroke Survivors: The Tele-Berg Balance Scale.
J Neurol Phys Ther
December 2024
Department of Physical Therapy, Motor Control Laboratory (LADECOM), Centre of Healthy and Sport Sciences, University of Santa Catarina State, Florianópolis, Santa Catarina, Brazil.
Background And Purpose: Telerehabilitation represents an alternative for individuals who have difficulty accessing services to receive care. Therefore, telerehabilitation measures must be studied for their reliability and validity. This study evaluated the validity and reliability of the videoconference-based Berg Balance Scale assessment in stroke survivors.
View Article and Find Full Text PDFEvaluation of the Short-Term Restorative Care program: Effects on physical functioning.
Australas J Ageing
December 2024
School of Nursing, Centre for Healthcare Transformation, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Objective: The Short-Term Restorative Care program is an 8-week multidisciplinary early intervention funded by the Australian Government that aims to reverse or slow the functional decline of older Australians. Despite the large investment of tax-payer money to fund the program, very little peer-reviewed literature exists examining the ability of the program to deliver on its aims.
Methods: This was a retrospective cohort study.
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