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Background infection (CDI) is a significant healthcare concern, marked by its rising prevalence and associated morbidity and mortality. However, there is limited data on the epidemiology of CDI in the eastern region of India. Objectives The study aims to determine the incidence of CDI among adult patients admitted to the inpatient department of a tertiary care hospital and identify the risk factors associated with CDI.
View Article and Find Full Text PDFInfections and Factors Associated with Recurrence.
Infect Dis Clin Microbiol
December 2024
Department of Medical Microbiology, Giresun University School of Medicine, Giresun, Türkiye.
Objective: is one of the leading causes of antibiotic-associated diarrhea. Recurrent infection (rCDI) is significant because of prolonged hospital stays, morbidity, and additional costs. Our study aimed to examine the characteristics of infections and investigate factors associated with recurrence.
View Article and Find Full Text PDFSay it ain't : a microbiology nudge comment leads to less treatment of respiratory colonization.
Infect Control Hosp Epidemiol
December 2024
Department of Pharmacy, Henry Ford Hospital, Detroit, MI, USA.
Objective: To describe the effect of a (SM) respiratory culture nudge on antibiotic use in colonized patients.
Design: IRB-approved quasi-experiment.
Setting: Five acute-care hospitals in Michigan.
The evidence for probiotics in the treatment of digestive disorders in the pediatric population.
J Gastroenterol Hepatol
November 2024
Department of Pathology, Tan Tock Seng Hospital, Singapore, Singapore.
Health claims for many probiotic-labeled products are poorly substantiated. This technical review addressed the clinical question: "Do probiotics have a role in the management of the following conditions in childhood?" Evidence supports efficacy for probiotic strains of Saccharomyces boulardii, Lactobacillus reuteri, and Lactobacillus rhamnosus GG for improving outcomes of acute gastroenteritis, of S. boulardii and L.
View Article and Find Full Text PDFNavigating antibiotic therapy in acute cholangitis: Best practices and new insights.
J Hepatobiliary Pancreat Sci
November 2024
Department of Gastroenterology, Medicine Center, Shonan Kamakura General Hospital, Kamakura, Japan.
Article Synopsis
- Antibiotic resistance globally causes increased health issues, costs, and mortality, highlighting the need for better antibiotic usage research, especially for treating acute cholangitis (AC), which often requires antimicrobial therapy.
- The Tokyo Guidelines 2018 suggest 4-7 days of antibiotics after biliary drainage, but this recommendation lacks strong evidence and is mainly based on expert opinions.
- Recent studies propose a shorter 1-3 day antibiotic treatment, prompting a reevaluation of treatment duration to improve effectiveness while minimizing resistance and side effects, taking into account local resistance patterns and patient-specific risks.
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