A linear and nonlinear causality detection method called the error-reduction-ratio causality (ERRC) test is introduced in this paper to investigate if linear or nonlinear models should be considered in the study of human electroencephalograph (EEG) data. In comparison to the traditional Granger methods, one significant advantage of the ERRC approach is that it can effectively detect the time-varying linear and nonlinear causalities between two signals without fitting a complete nonlinear model. Two numerical simulation examples are employed to compare the performance of the new method with other widely used methods in the presence of noise and in tracking time-varying causality. Finally, an application to measure the linear and nonlinear relationships between two EEG signals from different cortical sites for patients with childhood absence epilepsy is discussed.
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http://dx.doi.org/10.1109/TBME.2013.2269766 | DOI Listing |
PLoS One
January 2025
School of Artificial Intelligence and Information Technology, Nanjing University of Chinese Medicine, Nanjing, China.
Background: Previous studies have shown that both the composite dietary antioxidant index (CDAI) and sex are strongly associated with a variety of cardiovascular diseases, but sex differences between CDAI and hyperlipidemia are unknown.
Objective: This study utilized data from the National Health and Nutrition Examination Survey (NHANES) to investigate the sex differences between CDAI and hyperlipidemia.
Method: We calculated the CDAI of the six dietary antioxidants using data from NHANES, explored the relationship between CDAI and the prevalence of hyperlipidemia using multivariate logistic regression analysis, and analyzed for potential nonlinear associations using restricted cubic spline.
Medicine (Baltimore)
January 2025
Teaching Office, Second People's Hospital of Shenzhen (First Affiliated Hospital of Shenzhen University), Shenzhen City, China.
Previous studies have provided relatively limited evidence in examining the impact of preoperative serum albumin levels on the length of hospital stay (LOS) in patients with hip fractures. This study aimed to elucidate the association between preoperative serum albumin levels and LOS in elderly patients with hip fractures. This retrospective cohort study included 1444 elderly patients undergoing surgical treatment for hip fractures at the Second People's Hospital of Shenzhen from January 2012 to December 2021.
View Article and Find Full Text PDFJ Cogn Neurosci
January 2025
Queen's University, Kingston, Ontario, Canada.
Pupil responses are commonly used to provide insight into visual perception, autonomic control, cognition, and various brain disorders. However, making inferences from pupil data can be complicated by nonlinearities in pupil dynamics and variability within and across individuals, which challenge the assumptions of linearity or group-level homogeneity required for common analysis methods. In this study, we evaluated luminance evoked pupil dynamics in young healthy adults (n = 10, M:F = 5:5, ages 19-25 years) by identifying nonlinearities, variability, and conserved relationships across individuals to improve the ability to make inferences from pupil data.
View Article and Find Full Text PDFTher Drug Monit
February 2025
School of Pharmacy, University of Queensland, Brisbane, QLD, Australia.
Background: Therapeutic monitoring is routinely performed to ensure tacrolimus whole-blood concentrations fall within a predefined target. Despite this, patients still experience inefficacy and toxicity that could be related to variability in free (unbound) tacrolimus exposure. Therefore, the aim of this study was to compare tacrolimus-free plasma (C u ), total plasma (C p ), and whole-blood (C wb ) concentrations in adult kidney transplant recipients and to characterize tacrolimus disposition across different matrices.
View Article and Find Full Text PDFMinerva Urol Nephrol
January 2025
Department of Urology, The Second Affiliated Hospital of Shantou University Medical College, Shantou, China -
Background: The rising incidence of kidney stones underscores the imperative to devise effective preventive measures. While a robust association between cardiovascular disease (CVD) and kidney stones exists, the current research landscape lacks investigations between cardiovascular health (CVH) and kidney stones. This study aims to explore the association between CVH, assessed by Life's Essential 8 (LE8), and kidney stones, with the role of blood lipids and insulin resistance in this relationship.
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