An explanation for the vast difference observed in the trypanocidal activity between the new secondary (-methylated) hydroxamic acids and , and their primary (nonmethylated) congeners and , based on their / conformational behaviour in DMSO, is presented.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661977 | PMC |
| http://dx.doi.org/10.1016/j.tetlet.2013.03.128 | DOI Listing |
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