We report the case of a patient diagnosed with genitogluteal porokeratosis, a disorder of epidermal keratinization. The location described is extremely rare and very often late diagnosed or even misdiagnosed. Histopathology showed a typical cornoid lamella of great value to support this diagnosis. The importance of awareness of this entity by the specialist is emphasized as a differential diagnosis among genital diseases of chronic evolution and difficult treatment.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754380 | PMC |
| http://dx.doi.org/10.1590/ABD1806-4841.20131831 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Genital porokeratosis: A case report and review of pathogenesis and genitogluteal subtypes of porokeratosis.
SAGE Open Med Case Rep
January 2025
Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Porokeratosis is a condition characterized by abnormal epidermal keratinization with a unique morphology of papules or plaques surrounded by a thread-like border of scale corresponding to the cornoid lamella on histology. Many established subtypes have been described; however, genitogluteal porokeratosis is a rare entity. We present the case of a 58-year-old male with pruritic reddish lesions affecting the genitals and thighs, diagnosed with genital porokeratosis.
View Article and Find Full Text PDFPorokeratosis ptychotropica without genitogluteal involvement - A rare presentation.
Indian J Dermatol Venereol Leprol
July 2024
Department of Dermatology, Maharajgunj Medical Campus, Maharajgunj, Kathmandu, Nepal.
Genitogluteal porokeratosis with dystrophic calcinosis on the scrotum.
Ann Dermatol Venereol
September 2024
Department of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400011, China. Electronic address:
Porokeratoses-A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants.
Metabolites
November 2023
Melanoma and Skin Cancer Unit, Department of Dermatology, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile.
Porokeratosis is a heterogeneous group of keratinising disorders characterised by the presence of particular microscopic structural changes, namely the presence of the cornoid lamella. This structure develops as a consequence of a defective isoprenoid pathway, critical for cholesterol synthesis. Commonly recognised variants include disseminated superficial actinic porokeratosis, disseminated superficial porokeratosis, porokeratosis of Mibelli, palmoplantar porokeratosis (including porokeratosis palmaris et plantaris disseminata and punctate porokeratosis), linear porokeratosis, verrucous porokeratosis (also known as genitogluteal porokeratosis), follicular porokeratosis and porokeratoma.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!