AI Article Synopsis
- The development of artificial spores has become a significant research area, showing unique properties like slowing cell division and strong protection against various stresses, such as heat and UV radiation.
- These robust cell-in-shell structures serve as adaptable scaffolds for enhancing cells, making them useful in fields like tissue engineering and biosensors.
- Future research should aim for advanced engineering techniques, including responsive shell-degradation, multilayer designs with different functions, and the ability to encapsulate multiple cells within a single artificial spore.
Article Abstract
In this Opinion we discuss the development of artificial spores and their maturation as an independent field of research. The robust cell-in-shell structures have displayed unprecedented characteristics, which include the retardation of cell division and extensive cytoprotective capabilities that encompass exposure to osmotic pressure, shear force, heat, UV radiation, and lytic enzymes. Additionally, the nanothin shells act as highly versatile scaffolds for chemical functionalization to equip cells for implementation in tissue engineering, biosensors, cell therapy, or other biotechnological applications. We also explore the future direction of this emerging field and dictate that the next phase of research should focus on attaining more intricate engineering to achieve stimulus-responsive shell-degradation, multilayer casings with orthogonal functions, and the encapsulation of multiple cells for multicellular artificial spores.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.tibtech.2013.05.009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Germination and Growth of Two Strains of in Selected Hot Dishes After Cooking.
Foods
January 2025
Department of Animal Origin Food and Gastronomic Sciences, Faculty of Veterinary Hygiene and Ecology, University of Veterinary Sciences Brno, Palackého tř. 1946/1, 612 42 Brno, Czech Republic.
The aim of this study was to assess the germination and growth of two strains of following the artificial inoculation of six selected hot dishes with spores which were then stored at temperatures of 40, 50, and 60 °C for 0.5, 1.0, 2.
View Article and Find Full Text PDFSpoilage characteristics of sous-vide beef caused by Clostridium estertheticum.
Int J Food Microbiol
January 2025
Unit of Food Hygiene and Technology, Centre for Food Science and Veterinary Public Health, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210 Vienna, Austria.
The increasing popularity of sous-vide (SV) cooking necessitates research into the microbiological quality, sensory changes, and shelf life of SV products. Studies show that SV cooking significantly reduces the levels of meat microbiota and pathogens, positively affecting the shelf life and safety of SV products. However, the meat spoilage organism Clostridium estertheticum can survive SV cooking as it can produce heat-tolerant spores.
View Article and Find Full Text PDFContemporary prostate cancer radiation therapy trials may underestimate the risk of biochemical recurrence.
J Sex Med
December 2024
Sexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, United States.
Background: Radiotherapy is often given with androgen deprivation therapy for prostate cancer which causes a reduction in testosterone levels, which when below castrate levels, can cause the prostate specific antigen (PSA) levels to be artificially low.
Aim: To determine if high-level radiotherapy clinical trials are underestimating biochemical recurrence (BCR) rates due to inadequate measurement of testosterone levels.
Methods: The study plans for clinical trials performed by the Radiation Therapy Oncology Group (RTOG [now NRG]) on clinicaltrials.
Antifungal lipopeptides from the marine Bacillus amyloliquefaciens HY2-1: A potential biocontrol agent exhibiting in vitro and in vivo antagonistic activities against Penicillium digitatum.
Int J Biol Macromol
January 2025
College of Food Science and Technology, Guangdong Ocean University, Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Guangdong Provincial Engineering Technology Research Center of Seafood, Guangdong Province Engineering Laboratory for Marine Biological Products, Key Laboratory of Advanced Processing of Aquatic Product of Guangdong Higher Education Institution, Zhanjiang 524088, China. Electronic address:
This study aimed to clarify the antifungal activity and action mechanism of the lipopeptides from a marine Bacillus amyloliquefaciens HY2-1 against Penicillium digitatum both in vitro and in vivo. Results showed that HY2-1 lipopeptides exerted obvious inhibitions on spore germination and mycelium growth of P. digitatum.
View Article and Find Full Text PDFFirst report of causing postharvest fruit rot of sweet orange in Anhui province, China.
Plant Dis
December 2024
Hefei, China;
Article Synopsis
- Sweet oranges (Citrus sinensis cv. Newhall) are a popular cash crop known for their health benefits, but an outbreak of postharvest rot was reported in March 2024 in Anqing, China, affecting 15% to 20% of the fruit.
- The rot starts with small brown spots on the orange surface that expand and cause the fruit to decompose, leading to isolation and identification of the pathogen using specific sterilization and growth methods.
- Ten fungal isolates were confirmed to be Alternaria sp. through morphological and molecular techniques, with sequences deposited in GenBank, revealing a 100% nucleotide identity with Alternaria alternata sequences.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!