The purpose of this study is to find a useful mathematical model for multi-channel pulmonary sound data. Vector auto-regressive (VAR) model schema is adopted and the best set of arguments, namely, the order and sample size of the model and the sampling rate of the data, is aimed to be determined. Both conventional prediction error criteria and a set of three new criteria which are derived specifically for pulmonary sound signals are used to evaluate the success of the model. In terms of these criteria, the second order 250-point model is selected to be the most descriptive VAR model for 14-channel pulmonary sound data. The preferred sampling rate is the original data acquisition rate, which is 9600 samples per second. The effect of normalization of the data with respect to the air flow is also examined. Six normalization schemes are implemented on the data prior to the model fit, and the resulting model parameters are examined in terms of the proposed criterion measures. It is concluded that normalization with respect to flow is not necessary prior to the VAR modeling of pulmonary sound data.
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http://dx.doi.org/10.1016/j.cmpb.2013.05.007 | DOI Listing |
Acta Bioeng Biomech
June 2024
2Daping Hospital, Army Medical Center, Chongqing, China.
: This study explores how thoracic orientation affects lung pressure and injury outcomes from shock waves, building on earlier research that suggested human posture impacts injury severity. : A layered finite element model of the chest was constructed based on the Chinese Visual Human Dataset (CVH), including the rib and intercostal muscle layers. The dynamic response of the chest under 12 different angle-oriented shock waves under incident pressures of 200 kPa and 500 kPa was calculated.
View Article and Find Full Text PDFPhysiol Meas
January 2025
Nanchang University, 1st Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, 330031, CHINA.
Background And Objective: In contrast to respiratory sound classification, respiratory phase and adventitious sound event detection provides more detailed and accurate respiratory information, which is clinically important for respiratory disorders. However, current respiratory sound event detection models mainly use convolutional neural networks to generate frame-level predictions. A significant drawback of the frame-based model lies in its pursuit of optimal frame-level predictions rather than the best event-level ones.
View Article and Find Full Text PDFFront Oncol
January 2025
Department of Head and Neck Surgery, Gansu Provincial Cancer Hospital, Lanzhou, China.
Purpose: Investigating the diagnosis and treatment of bilateral Chylothorax after neck lymph node dissection for thyroid cancer.
Methods: The clinical data of a patient with bilateral chylothorax after neck lymph node dissection for thyroid cancer were retrospectively analyzed, and the relevant literature was reviewed.
Results: The patient underwent a total thyroidectomy and left neck lymph node dissection, with no evidence of lymph fluid leakage observed during the operation.
Nat Commun
January 2025
Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL, USA.
Assembly of actin-based stereocilia is critical for cochlear hair cells to detect sound. To tune their mechanosensivity, stereocilia form bundles composed of graded rows of ascending height, necessitating the precise control of actin polymerization. Myosin 15 (MYO15A) drives hair bundle development by delivering critical proteins to growing stereocilia that regulate actin polymerization via an unknown mechanism.
View Article and Find Full Text PDFStat Med
February 2025
Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut, USA.
With the increasing maturity of genetic profiling, an essential and routine task in cancer research is to model disease outcomes/phenotypes using genetic variables. Many methods have been successfully developed. However, oftentimes, empirical performance is unsatisfactory because of a "lack of information.
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