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Collagen/polyvinyl alcohol scaffolds combined with platelet-rich plasma to enhance anterior cruciate ligament repair.
Biomater Adv
December 2024
College of Biological Science and Engineering, Fuzhou University, No. 2 Xueyuan Road, Fuzhou 350108, China; Fujian Key Laboratory of Medical Instrument and Pharmaceutical Technology, Fuzhou University, No. 2 Xueyuan Road, Fuzhou 350108, China. Electronic address:
In anterior cruciate ligament (ACL) repair methods, the continuous enzymatic erosion of synovial fluid can impede healing and potentially lead to repair failure, as well as exacerbate articular cartilage wear, resulting in joint degeneration. Inspired by the blood clot during medial collateral ligament healing, we developed a composite scaffold comprising collagen (1 %, w/v) and polyvinyl alcohol (5 %, w/v) combined with platelet-rich plasma (PRP). The composite scaffold provides a protective barrier against synovial erosion for the ruptured ACL, while simultaneously facilitating tissue repair, thereby enhancing the efficacy of ACL repair techniques.
View Article and Find Full Text PDF[Acute non-traumatic single-articular pain].
Rev Med Suisse
September 2024
Service de médecine de premier recours, Hôpitaux universitaires de Genève, 1211 Genève 14.
Article Synopsis
- The main non-traumatic causes of acute single-joint pain include microcrystalline, degenerative, reactive, and septic arthritis, with septic arthritis needing quick exclusion through joint effusion puncture.
- If there’s no sepsis, surgical drainage should be done within 24 hours of admission.
- For conditions like gout and reactive arthritis, imaging and urate-lowering treatments are recommended, while osteoarthritis management emphasizes self-care strategies for pain relief.
Late Presentation of Primary Oxalosis, Microcrystalline Arthropathy, and Tumoral Calcinosis: A Case Report and a Literature Review.
Curr Rheumatol Rev
June 2024
Department of Nephrology, Dialysis, and Transplantation, Hedi Chaker University Hospital, Sfax, Tunisia.
Article Synopsis
- Primary hyperoxaluria is a genetic disorder affecting the glyoxylate pathway, leading to poor oxalate breakdown and complications like kidney and joint diseases, with neonatal oxalosis being the most severe form.
- A 55-year-old male on hemodialysis for end-stage renal failure and diagnosed with primary hyperoxaluria presented with inflammatory joint issues and various calcifications, but his condition continued to worsen despite treatment.
- The case highlights that primary hyperoxaluria can have late-onset symptoms and long-term complications beyond kidney issues, contributing to a complex medical picture.
Anterior Chest Wall Non-traumatic Arthropathies: A Crucial but Often Overlooked Site.
Curr Rheumatol Rev
January 2024
Department of Rheumatology, Kassab Orthopedics Institute, Ksar Saïd, Tunisia.
Objective: The purpose of this study was to describe the distribution of Anterior Chest Wall (ACW) arthropathies in a tertiary care center and identify clinical, biological and imaging findings to differentiate osteoarthritis (OA) from non-osteoarthritis (N-OA) etiologies.
Methods: Search from medical records from January 2009 to April 2022, including patients with manubriosternal and/or sternoclavicular and/or sternocostal joint changes confirmed by ultrasonography, computed tomography or magnetic resonance imaging. The final study group was divided into OA and N-OA subgroups.
Joint manifestations revealing inborn metabolic diseases in adults: a narrative review.
Orphanet J Rare Dis
August 2023
Department of Internal Medicine, University Hospital of Tours, Tours, France.
Inborn metabolic diseases (IMD) are rare conditions that can be diagnosed during adulthood. Patients with IMD may have joint symptoms and the challenge is to establish an early diagnosis in order to institute appropriate treatment and prevent irreversible damage. This review describes the joint manifestations of IMD that may be encountered in adults.
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