The article presents the results of evaluation of features of the structural organization of microvascular complexes of muscular fascicles and glands in the prostate of men of different ages. Autopsy material of 103 human prostate was used for examination. The data on the structural transformation of glands, muscle cells and connective tissue components in human prostate suggests that at different age periods the growth and differentiation of various structures occur unevenly, constantly changing relationships between components of organ and parts of its circulatory bed. Circulatory bed of prostate is developed and transformed according to the needs of structures perfused. Age involution processes in the prostate and circulatory bed develop irrespective of man's age and are individual in nature. The general trend of involutional changes of prostate histology suggests that the involution begins within paravasal zones. It seems that the reason is increase the hydrodynamic pressure on the venous bed of prostate.
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