AI Article Synopsis
- The study investigates the clinical features and prognostic factors of 178 thyroid carcinoma patients treated at İzmir Atatürk Training Hospital between 2010 and 2011.
- Findings indicate that factors such as tumor size, vascular invasion, and thyroglobulin levels significantly impact the risk of metastasis, while gender and age did not show significant differences across patient groups.
- The results suggest that while certain characteristics are correlated with prognosis, the overall impact of age and gender on patient outcomes in thyroid cancer is minimal.
Article Abstract
Aim Of The Study: Thyroid carcinoma is the most common malignancy of endocrine organs. The prognosis varies. Factors such as age, sex, size of the tumor, stage of disease, presence of extrathyroidal spread, and completeness of resection have been found to significantly influence prognosis. We aimed to evaluate clinical features of our patients with thyroid carcinoma, prospectively.
Material And Methods: We evaluated total 178 patients treated between 2010 and 2011 at the Department of Endocrinology, İzmir Atatürk Training Hospital, retrospectively. Data on patients, tumors, and therapeutic approaches were collected. All results are shown as mean ± standard deviation (SD). P values were based on two-sided tests with a cutoff for statistical significance of 0.05 and 95% confidence interval.
Results: There were no differences between female and male patients according to histopathological subtypes, demographic data and prognostic findings of thyroid cancer. The assessment of tumor size and other prognostic factors revealed that there was a correlation between tumor size and capsular and/or vascular invasion. In the postoperative evaluation we detected a correlation between metastases and vascular invasion and/or capsular invasion but there was no significant relation between focus (solitary/multifocal) and metastases.
Conclusion: There was no significant difference in terms of gender and age (< 45 years of age and ≥ 45 years of age) among the patient groups (low risk/intermediate risk/high risk). By multiple regression analysis among metastasis and prognostic factors it was observed that vascular invasion and thyroglobulin levels affect development of metastases.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687411 | PMC |
| http://dx.doi.org/10.5114/wo.2012.29288 | DOI Listing |
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