The paper was conducted sonographic study of extracranial atherosclerotic vascular changes in patients with diabetes mellitus, and lipid profile study of the dynamics under the influence of treatment with the inclusion of the drug "Reytoil". Structural changes of the vascular wall correlates with changes of lipid profile in patients with diabetes. Structural assessment of intima-media complex (IMC) can be used as a marker for early diagnosis of vascular remodeling in patients with diabetes, as well as the criterion of efficiency of a treatment. Detection of lipid exchange and evaluation of IMC in the early stages of diabetes mellitus will make it possible pathogenetic approach to providing comprehensive treatment of diabetes with dyslipidemia, including the drug "Reytoil".
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Curr Opin Infect Dis
January 2025
Department of Medicine, Clínica Rotger Quironsalud, Palma de Mallorca, Spain.
Purpose Of Review: Optimal duration of therapy in SSTIs - a heterogeneous group of infections - remains unknown. The advances in knowledge of antibiotic duration of treatment in selected SSTIs that can impact clinical practice and published in the last 18 months are reviewed.
Recent Findings: Recent evidence indicates that few patients receive guideline concordant empiric antibiotics and appropriate duration in the United States, although this likely can be extrapolated to other countries.
Front Public Health
January 2025
Rajavithi Hospital, College of Medicine, Ministry of Public Health, Rangsit University, Bangkok, Thailand.
Objective: This study aimed to assess the financial impact of different adoption rates of insulin glargine (IGlar) treatment compared to isophane protamine (neutral protamine hagedorn [NPH]) insulin treatment for patients with type-2 diabetes (T2D) and severe hypoglycemia in Thailand from the payer's perspective.
Methods: The budget impact analysis (BIA) model over a period of 5 years was used to estimate the net budget impact (NBI) of IGlar treatment by comparing the total budget expenditures under two scenarios: scenario 1 involved only NPH insulin and scenario 2 included the introduction of IGlar. The total budget included either the cost of insulin or a combination of the costs of insulin and the expense related to severe hypoglycemia.
J Multimorb Comorb
January 2025
Department of Health Systems and Policy, Kamuzu University of Health Sciences, Blantyre, Malawi.
Background: Multimorbidity is a growing global concern, affecting patient outcomes and healthcare costs. In low- and middle-income countries, data on multimorbidity in primary care beyond prevalence is limited. Our study explored the demographic and clinical characteristics of multimorbidity among older people attending primary health care in Malawi.
View Article and Find Full Text PDFDigital health interventions (DHIs), such as apps, websites and wearables, are being presented as solutions or enablers to manage the burden of cardiometabolic disease in healthcare. However, the potential benefits of DHIs may not be reaching the most in-need populations, who may face intersecting barriers to accessing health services and digital solutions. The Digital Interventions for South Asians in Cardiometabolic Disease (DISC) study used a mixed-method approach to focus on people of a South Asian background, a high-risk group for cardiometabolic disease.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama, Japan.
Several decades have passed since the description of the first patient with primary aldosteronism (PA). PA was initially classified in two main forms: aldosterone-producing adenoma (APA) and idiopathic hyperaldosteronism (IHA). However, the pathogenesis of PA has now been shown to be far more complex.
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