Four weeks after elective embolisation of a symptomatic benign uterine fibroid, a lady presented to her general practitioner with facial twitching and severe lassitude. Acute hypocalcaemia was diagnosed. Further investigations demonstrated hypomagnesaemia. Parathyroid hormone (PTH) was within normal limits. Symptoms and the acute metabolic disturbance resolved with treatment by oral magnesium and calcium supplementation. While lassitude is a common symptom of postfibroid embolisation and may last for up to 6 weeks, the presentation with facial twitching alerted the clinician to a potential electrolyte or metabolic imbalance. This is a first reported case of hypomagnesaemia associated with PTH resistance leading to hypocalcaemia precipitated by alcohol particle embolisation for benign fibroid disease.
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http://dx.doi.org/10.1136/bcr-2013-008708 | DOI Listing |
Ann Endocrinol (Paris)
January 2025
Service d'Endocrinologie, Diabétologie, Métabolisme, Nutrition; Hôpital Huriez, CHU Lille; Inserm U1190, Institut Génomique Européen pour le Diabète, Université de Lille, F-59000 Lille, France. Electronic address:
The differential diagnosis of primary hyperparathyroidism can be considered clinically, biologically and radiologically. Clinically, primary hyperparathyroidism should be suspected in case of diffuse pain, renal lithiasis, osteoporosis, repeated fracture, cognitive or psychiatric disorder, or disturbance of consciousness. Nevertheless, the differential diagnosis of primary hyperparathyroidism is mainly biological, particularly in atypical forms, which must be differentiated from hypercalcemia with hypocalciuria or non- elevated PTH on the one hand, and from normo-calcemia with elevated PTH, hypophosphatemia or hypercalciuria on the other.
View Article and Find Full Text PDFIntroduction: Pseudohypoparathyroidism 1A (PHP1A) is the best-known representative of inactivating PTH/PTHrP signaling disorders (iPPSD). The associated phenotype develops over time and often includes hormonal resistances, short stature and osteoma cutis. More complex and very early manifestations have also been reported.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Medical Physiology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
Background: Castration of adult male rats led to the development of osteoporosis. Oxidative stress and inflammatory factors have been identified as potential causative factors. Notably, oxymatrine (OMT) possesses potent anti-inflammatory and antioxidant activities.
View Article and Find Full Text PDFJ Diabetes Metab Disord
June 2025
Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.
Background: Middle Eastern (ME) immigrants to Europe have a heavy burden of metabolic disorders including a higher prevalence of insulin resistance, T2D and obesity as compared to native-born Europeans. Vitamin D insufficiency and deficiency are prevalent conditions in people originating from the ME.
Aims: To study the differences in the levels of 25(OH)D and parathyroid hormone (PTH) across ME and European ethnicity, and the effect of 25(OH)D and PTH on insulin action and secretion.
Nanotechnology
December 2024
Chemistry and Biochemistry, North Carolina Central University, Durham, NC 27707, United States of America.
Ciprofloxacin (CIP) is a widely used antibiotic, and its presence in water bodies poses a risk due to its resistance to conventional wastewater treatment processes. The accumulation of such pharmaceuticals can disrupt aquatic ecosystems, harm aquatic life, and contribute to ecological imbalances. Therefore, the degradation of CIP is of immense environmental significance.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!