Transposases, enzymes that catalyze the movement of mobile genetic elements, are the most abundant genes in nature. While many bacteria encode an abundance of transposases in their genomes, the current paradigm is that the expression of transposase genes is tightly regulated and generally low due to its severe mutagenic effects. In the current study, we detected the highest number of transposase proteins ever reported in bacteria, in symbionts of the gutless marine worm Olavius algarvensis with metaproteomics. At least 26 different transposases from 12 different families were detected, and genomic and proteomic analyses suggest that many of these are active. This high expression of transposases indicates that the mechanisms for their tight regulation have been disabled or no longer exist.
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| http://dx.doi.org/10.1128/mBio.00223-13 | DOI Listing |
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Article Synopsis
- Marine plastispheres are dynamic microhabitats where microorganisms thrive on plastic debris, but their initial formation and interactions are not well understood.
- This study used metaproteomic and metagenomic techniques to investigate the microbial diversity and biofilm development on low-density polyethylene (LDPE) over 3 and 7 days, identifying key organisms like Pseudomonas and Marinomonas.
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