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The detection of antibodies to the Angiotensin II-type 1 receptor in transplantation. | LitMetric

The detection of antibodies to the Angiotensin II-type 1 receptor in transplantation.

Methods Mol Biol

Clinic for Nephrology and Intensive Care Medicine, Charité-Campus Virchow-Klinikum, Berlin, Germany.

Published: February 2014

The detection of auto-antibodies detection is a major aspect of patient's immunomonitoring. Antibodies directed against the heart and kidney Angiotensin II type 1 receptor (AT1R) play a major role in antibody mediated rejection after heart and kidney transplantation and in obliterative vasculopathy of autoimmune diseases. Here, a sandwich enzyme-linked immunosorbent assay (ELISA) is the reliable tool for the detection of auto-antibodies targeting AT1R.

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Source
http://dx.doi.org/10.1007/978-1-62703-493-7_19DOI Listing

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