Differences of the bacterial population of home- and daycared children are more significant within the nose than in the pharynx. In vitro the efficiency of erythromycine against bacteria of the nose-pharynx-area is broader then that of Penicilline and the combination Trimethoprime plus Sulfonamide.
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Antimicrob Resist Infect Control
January 2025
Department of Pediatrics, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, Republic of Korea.
Background: Clinical characteristics and outcomes of carbapenem-resistant Enterobacterales (CRE) infection and colonization have rarely been reported in patients with severe burns, who are prone to severe bacterial infections. This study aimed to evaluate clinical characteristics and outcomes of CRE infection and colonization in patients with severe burns.
Methods: The characteristics of 106 episodes of CRE acquisition (infection or colonization) in 98 patients with severe burns were evaluated by a retrospective medical record review.
Microbiome
January 2025
Department of Medicine, University of Toronto, Toronto, Canada.
Background: Genital inflammation increases HIV susceptibility and is associated with the density of pro-inflammatory anaerobes in the vagina and coronal sulcus. The penile urethra is a critical site of HIV acquisition, although correlates of urethral HIV acquisition are largely unknown. While Streptococcus mitis is a consistent component of the urethral flora, the presence of Gardnerella vaginalis has been linked with prior penile-vaginal sex and urethral inflammation.
View Article and Find Full Text PDFDtsch Med Wochenschr
February 2025
German surveillance data from 2022 reported a prevalence of nosocomial infections among hospitalized patients of 5,2%. Clostridioides-difficile-infections (CDI) are the most frequent cause of nosocomial diarrhea. They are usually caused by antibiotic exposure and the subsequent changes in the gut microbiota.
View Article and Find Full Text PDFMicrob Genom
January 2025
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, USA.
Members of the phylum inhabit a wide range of ecosystems including soils. We analysed the global patterns of distribution and habitat preferences of various lineages across major ecosystems (soil, engineered, host-associated, marine, non-marine saline and alkaline and terrestrial non-soil ecosystems) in 248 559 publicly available metagenomic datasets. Classes , , and were highly ubiquitous and showed a clear preference to soil over non-soil habitats, while classes and showed preferences to non-soil habitats.
View Article and Find Full Text PDFmBio
January 2025
Department of Integrative Biology, University of California, Berkeley, Berkeley, California, USA.
The composition of the gut microbiome is determined by a complex interplay of diet, host genetics, microbe-microbe interactions, abiotic factors, and stochasticity. Previous studies have demonstrated the importance of host genetics in community assembly of the gut microbiome and identified a central role for DBL-1/BMP immune signaling in determining the abundance of gut . However, the effects of DBL-1 signaling on gut bacteria were found to depend on its activation in extra-intestinal tissues, highlighting a gap in our understanding of the proximal factors that determine microbiome composition.
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