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Formal Thought Disorder in Schizophrenia: A Problematic History.

Schizophr Bull

January 2025

Department of Psychiatry, University of Oxford, and Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX37JX, United Kingdom.

Background And Hypothesis: Formal thought disorder (FTD), studied even before the inception of the concept of schizophrenia, remains a deeply isolating experience for patients as well as a difficult one for their interlocutors, including clinicians.

Study Design: The views on language, paralinguistic, and extralinguistic features exhibited by patients with severe mental ill health are reviewed, including the contributions from 19th-century European authors to the last third of the 20th century.

Study Results: Stages in the construction of FTD are described, including its merging with Dementia Praecox, and its subsequently being shaped by notions such as primitive archaic thinking, paralogical or autistic thinking, concretism, overinclusive thinking, and the return of the efforts to describing it with increased reliability.

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Objective: Patients with schizophrenia value improved life engagement, a term that describes positive health aspects across emotional, physical, social, and cognitive domains. This analysis of clinical trial data aimed to investigate the effect of brexpiprazole on patient life engagement in schizophrenia over the short and long term.

Methods: Data were pooled from three 6-week, randomized, double-blind, placebo-controlled clinical trials (ClinicalTrials.

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Background: Health-related quality of life is a multi-dimensional concept that involves individual's perceived physical and mental health, social relationships, and environment. Family members are the primary caregivers of people living with schizophrenia in China, the quality of life of caregiver of people living with schizophrenia is generally poorer, which may indirectly affect the quality of life of the people with schizophrenia.

Methods: We conducted a comprehensive survey on quality of life in caregivers of people living with schizophrenia based on the Schizophrenia-specific cohort in the Less-developed Multi-ethnic Region of Southwest China to validate the accessibility and effectiveness of the schizophrenia family care model at the family level, caregivers of people living with schizophrenia were selected as participants in Baoshan City, Yunnan Province from September 2022 to March 2023, quality of life, family burden of disease, sociodemographic and behavioral information of participants were collected.

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Background: There is a complex relationship between tobacco use and pain. Nicotine provides temporary pain relief but increases the risk of chronic pain. This study aimed to investigate use of tobacco for pain relief and its association with demographic and medical characteristics in Japan.

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Surviving the 2021 heat dome with schizophrenia: A qualitative, interview-based unpacking of risks and vulnerabilities.

Soc Sci Med

December 2024

Department of Psychiatry, Faculty of Medicine, University of British Columbia, B.C. Mental Health and Substance Use Services, Provincial Health Services Authority, Vancouver, BC, Canada.

This study explores the multifaceted challenges experienced by individuals with schizophrenia during extreme heat, highlighting the interplay between individual factors, social dynamics, and environmental influences. Despite making up only 1% of the Canadian population, individuals diagnosed with schizophrenia comprised 16% (n = 97) of the deaths during the 2021 heat dome in Western Canada. However, to date, there exists scant qualitative research that explore the direct experiences and the intricacies of intersecting factors faced by individuals with schizophrenia during extreme heat events.

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