Short anagen syndrome (SAS) is a recently described entity characterized by idiopathic shortening of anagen phase. The condition is poorly described in Indian population. We describe the 1(st) Indian case with clinico-pathological features of a 30-year-old woman diagnosed with SAS. Case was diagnosed on the basis of clinical examination, trichogram, microscopic examination of the hair shaft, histopathologic examination of scalp, and measurement of hair growth rate.
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http://dx.doi.org/10.4103/0974-7753.111200 | DOI Listing |
Skinmed
October 2024
Department of Dermatology, Mater Dei Hospital, Msida, Malta.
A 10-year-old healthy, Caucasian girl presented in May 2021 with short and thin scalp hair since birth (Figures 1A-C). She had achieved all of her developmental milestones, and her parents denied any similar family history. She had only two hair cuts in the past, which were performed to trim long hair over the midscalp to have a uniform length.
View Article and Find Full Text PDFTransl Pediatr
July 2024
Department of Endocrinology, Children's Hospital of Capital Institute of Pediatrics, Beijing, China.
Transgenic Res
October 2024
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
We report the generation and characterization of the K5: CAT bigenic mouse in which the constitutively activated form of β-catenin (ΔN89 β-catenin) is conditionally expressed in cytokeratin-5 (K5) positive epidermal keratinocytes. Following short-term doxycycline intake during the telogen resting phase, the adult K5: CAT bigenic develops enlarged pilosebaceous units that expand deep into the dermis, an expansion usually observed during the anagen growth phase. Prolonged doxycycline treatment results in significant thickening and folding of the K5: CAT epidermis.
View Article and Find Full Text PDFPharmaceutics
July 2024
Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310015, China.
Androgenetic alopecia (AGA) is a highly prevalent condition in contemporary society. The conventional treatment of minoxidil tincture is hindered by issues such as skin irritation caused by ethanol, non-specific accumulation in hair follicles, and short retention due to its liquid form. Herein, we have developed a novel minoxidil-incorporated engineered exosomes biopotentiated hydrogel (Gel@MNs) that has the capability to modulate the perifollicular microenvironment for the treatment of AGA.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
November 2024
Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
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