The folding of DNA molecules by DNA origami is used in a nanosensor to analyze enzymatic DNA repair activity of hAGT. The method uses conformational changes that condition α-thrombin interaction with DNA aptamers, and illustrates the use of DNA origami as a proteinrecognition biosensor.

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201301293DOI Listing

Publication Analysis

Top Keywords

dna origami
12
dna repair
8
dna
7
origami dna
4
repair nanosensor
4
nanosensor single-molecule
4
single-molecule level
4
level folding
4
folding dna
4
dna molecules
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!