Competition between tuftsin and HBV S-protein sequences.

Int J Pept Protein Res

Institute of Chemistry, Wrocław University, Poland.

Published: May 1990

The syntheses of HBV S-protein partial sequences: Thr-Lys-Pro-Thr (I), Thr-Lys-Pro-Thr-Asp (II), and Thr-Lys-Pro-Thr-Asp-Gly (III) and also of pentapeptide Thr-Lys-Pro-Gly-Arg (IV), are described. For the peptides II and III inhibitory activity against tuftsin was found. Peptide IV (an analogue of tuftsin-inhibitor Thr-Lys-Pro-Pro-Arg) demonstrated a tuftsin-like activity in the phagocytosis experiments.

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http://dx.doi.org/10.1111/j.1399-3011.1990.tb00069.xDOI Listing

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