Background: To introduce a new technique to create a pulmonary valve biorifice for the reconstruction of the right ventricular outflow tract in tetralogy of Fallot (TOF), and to summarize the initial clinical experiment.
Methods: The new technique of reconstructing the right ventricular outflow tract with pulmonary valve biorifice was used in 53 cases of TOF (the observation group). While the conventional technique for reconstructing the right ventricular outflow tract was used in other 50 cases of TOF (the control group). The clinical Data of all cases was reviewed retrospectively.
Results: The ages, weights, cardiopulmonary bypass time, cardiac arrest time, as well as the post operation ventilation support time were not different significantly between groups. Unlike patients in the control group, patients from the observation group had shorter duration of ICU stay. Post- operation, in the observation group, only 2 cases had a large amount of pleural effusion, 1 case had mid-level effusion and 8 cases had a small amount of pleural effusion. While in the control group, there was 1 case of a large amount of effusion, 5 cases of mid-level effusion and 17 cases of a small amount of pleural effusion. 1 week after the operation, all patients were rechecked by echocardiography and no evidence of pulmonary valve stenosis was found. In the observation group, moderate pulmonary valve regurgitation was found in 8 cases, and mild regurgitation was observed in 15 cases. In the control group, severe regurgitation was observed in 3 cases, moderate regurgitation in 17 cases, and mild regurgitation in 16 cases. 33 cases from the observation group were rechecked six months, post-operation, and moderate-mild pulmonary regurgitation was found in 3 cases. As a follow up, 18 cases from the observation group were rechecked 1 year later, and no pulmonary regurgitation was found.
Conclusion: The new technique to create pulmonary valve biorifice can reduce the pulmonary valve regurgitation, reduce postoperative pleural effusion, and improve the early surgical outcome.
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http://dx.doi.org/10.1186/1749-8090-8-152 | DOI Listing |
Circ Res
January 2025
Division of Cardiology, Department of Medicine, Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, PA. (R.A.C., C.C.C., R.W., A.C., C.B., C.R., W.J.M., M.J. Bashline, A.P., A.M.P., P.B., M.J. Brown, C.S.H.).
Background: Calcific aortic valve disease is the pathological remodeling of valve leaflets. The initial steps in valve leaflet osteogenic reprogramming are not fully understood. As TERT (telomerase reverse transcriptase) overexpression primes mesenchymal stem cells to differentiate into osteoblasts, we investigated whether TERT contributes to the osteogenic reprogramming of valve interstitial cells.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Department of Center for Pulmonary Vascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Rationale: The transcatheter closure and atrioseptopexy are the main treatment methods for atrial septal defect (ASD). However, persistent hypoxemia due to iatrogenic diversion of inferior vena cava (IVC) to the left atrium (LA) is reported as a rare complication after ASD closure. Contrast echocardiology is a reliable and powerful tool to detect iatrogenic diversion and identify the etiology accurately.
View Article and Find Full Text PDFMultimed Man Cardiothorac Surg
January 2025
Maria Fareri Children's Hospital, Westchester Medical Center, Valhalla, NY, USA.
An 8-week-old, 3.4-kg infant, who was diagnosed prenatally with tetralogy of Fallot and absent pulmonary valve syndrome, was intubated after birth and failed extubation due to severe tracheobronchomalacia. He was deemed inoperable prior to being transferred to our institution.
View Article and Find Full Text PDFAnn Pediatr Cardiol
December 2024
Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Absent pulmonary valve syndrome, commonly linked with tetralogy of Fallot and ventricular septal defect, is a rare congenital condition. It is exceedingly rare to have an isolated absent pulmonary valve with an intact ventricular septum without cardiovascular shunt lesions, such as an atrial/ventricular septal defect or patent ductus arteriosus. This report presents a case of such rarity involving a young child with recurrent lower respiratory tract infections.
View Article and Find Full Text PDFCatheter Cardiovasc Interv
January 2025
Department of Pediatric Cardiology, Hotel Dieu de France University Medical Center, Saint Joseph University, Beirut, Lebanon.
Background: Pulmonary artery banding (PAB) palliates pulmonary over-circulation, while endovascular debanding (ED) offers a less invasive alternative to repeat surgery.
Objectives: To evaluate our experience with ED.
Aims: Retrospective review of single-center data (2015-2023) on children with single, multiple, or "Swiss-cheese" muscular ventricular septal defects (MVSDs) undergoing ED.
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