Laboratory testing for platelet antibodies.

Am J Hematol

Department of Pathology, University of Utah Health Sciences Center, and ARUP Laboratories Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA.

Published: September 2013

Laboratory testing for immune-mediated thrombocytopenias involves identification and classification of antibodies present in patient sera or attached to patient platelets. This article summarizes the available types of platelet antibody testing and applications in disorders such as neonatal alloimmune thrombocytopenia, post-transfusion purpura, multiple platelet transfusion refractoriness, immune thrombocytopenia, and drug-induced thrombocytopenia.

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajh.23503DOI Listing

Publication Analysis

Top Keywords

laboratory testing
8
testing platelet
4
platelet antibodies
4
antibodies laboratory
4
testing immune-mediated
4
immune-mediated thrombocytopenias
4
thrombocytopenias involves
4
involves identification
4
identification classification
4
classification antibodies
4

Similar Publications

Dating the bacterial tree of life based on ancient symbiosis.

Syst Biol

January 2025

Simon F. S. Li Marine Science Laboratory, School of Life Sciences and State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR.

Obtaining a timescale for bacterial evolution is crucial to understand early life evolution but is difficult owing to the scarcity of bacterial fossils. Here, we introduce multiple new time constraints to calibrate bacterial evolution based on ancient symbiosis. This idea is implemented using a bacterial tree constructed with genes found in the mitochondrial lineages phylogenetically embedded within Proteobacteria.

View Article and Find Full Text PDF

The Nozaki-Hiyama-Kishi reaction offers effective and reliable strategies for the preparation of alcohols via carbon-carbon bond formation. Typical methods usually require stoichiometric amounts of chromium salts, co-transition metals, and auxiliary reagents, which limits their practical application in industrial chemistry. To mitigate these limitations, substantial efforts have been made to develop chromium-catalytic approaches.

View Article and Find Full Text PDF

In regulatory aquatic risk assessment, toxicokinetic-toxicodynamic (TKTD) methods, such as the generalized unified threshold model of survival (GUTS), are already established and considered ready for use, whereas TKTD methods for aboveground terrestrial species, like arthropods, are less developed and currently not intended for risk assessment. This could be due to the fact that exposure in aboveground terrestrial systems is more event-based (feeding, contact, overspray, etc.), whereas exposure in aquatic systems is simply related to substance concentrations in the surrounding water.

View Article and Find Full Text PDF

Cardiac Lymph Flow Features and New Opportunities for Their Experimental Visualization.

Dokl Biochem Biophys

January 2025

Laboratory of Microangiopathic Mechanisms of Atherogenesis, St. Petersburg State University, St. Petersburg, Russia.

The aim of this study was to describe the features of myocardial lymph flow using a new combined method of visualization of the lymphatic system. The study was performed on pig hearts harvested from a local slaughterhouse. The original dye, consisting of lipid-soluble chlorophyll and lipiodol, was injected stepwise into the lymphatic vessels.

View Article and Find Full Text PDF

Background: Chronic infection with hepatitis B virus and HIV causes significant morbidity and mortality. Effective antiviral treatment is available for both. Ireland has historically been considered a low prevalence country.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!