Transient osteoporosis of the hip: A case report.

J Can Chiropr Assoc

Intern, Chiropractic Program, D'Youville College, Buffalo, NY.

Published: June 2013

We report a case of transient osteoporosis of the hip (TOH) in a 59-year-old man including the clinical presentation, diagnostic studies, management and clinical progress. TOH is a rare self-limiting condition that typically affects middle-aged men or, less frequently, women in the third trimester of pregnancy. Affected individuals present clinically with acute hip pain, limping gait, and limited ranges of hip motion. TOH may begin spontaneously or after a minor trauma. Radiographs are typically unremarkable but MR imaging studies yield findings consistent with bone marrow edema. TOH is referred to as regional migratory osteoporosis if it travels to other joints or the contralateral hip. TOH often resembles osteonecrosis but the two conditions must be differentiated due to different prognoses and management approaches. The term TOH is often used interchangeably and synonymously with transient bone marrow edema.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661178PMC

Publication Analysis

Top Keywords

transient osteoporosis
8
osteoporosis hip
8
hip toh
8
bone marrow
8
marrow edema
8
toh
6
hip
5
hip case
4
case report
4
report report
4

Similar Publications

Angelica gigas Nakai (AGN) root is a medicinal herbal widely used in traditional medicine in Korea. AGN root ethanolic extracts have been marketed as dietary supplements in the United States for memory health and pain management. We have recently reviewed the pharmacokinetics (PK) and first-pass hepatic metabolism of ingested AGN supplements in humans for the signature pyranocoumarins decursin (D, C 1x), decursinol angelate (DA, C ~ 10x) and their common botanical precursor and hepatic metabolite decursinol (DOH, C ~ 1000x).

View Article and Find Full Text PDF

We present a case of a 73-year-old woman with a medical history significant for hyperlipidemia, on pravastatin, who developed Takotsubo cardiomyopathy following a diagnosis of osteoporosis. She presented to the Emergency Department with acute transient left arm pain that resolved spontaneously. Investigations revealed elevated troponin levels, non-specific electrocardiographic changes, no significant coronary artery disease on angiography, and left ventricular systolic dysfunction, findings consistent with Takotsubo cardiomyopathy.

View Article and Find Full Text PDF
Article Synopsis
  • Transient osteoporosis (TO) is a temporary bone condition that commonly occurs in the third trimester of pregnancy, characterized by knee pain in some cases.
  • A case study of a 38-year-old pregnant woman showed significant knee pain for 8 weeks, diagnosed as TO, which resolved completely within a few months.
  • Healthcare providers should consider TO as a possible diagnosis for knee pain in pregnant women.
View Article and Find Full Text PDF

TMEM16A, a key calcium-activated chloride channel, is crucial for many physiological and pathological processes such as cancer, hypertension, and osteoporosis, etc. However, the regulatory mechanism of TMEM16A is poorly understood, limiting the discovery of effective modulators. Here, we unveil an allosteric gating mechanism by presenting a high-resolution cryo-EM structure of TMEM16A in complex with a channel inhibitor that we identified, Tamsulosin, which is resolved at 2.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!