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| http://dx.doi.org/10.3201/eid1903.121150 | DOI Listing |
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Clinical characteristics, progression patterns and treatment outcomes in microsporidial keratoconjunctivitis: a prospective study in Thailand.
Int Ophthalmol
November 2024
Department of Ophthalmology, Phramongkutklao Hospital, 315 Ratchawithi Road, Thung Phayathai Subdistrict, Ratchathewi, Bangkok, 10400, Thailand.
Purpose: To assess the clinical characteristics, progression patterns, and treatment outcomes of microbiologically confirmed microsporidial keratoconjunctivitis (MKC).
Methods: This prospective cross-sectional study included patients with superficial punctate epithelial keratitis clinically suspected of MKC. Comprehensive slit-lamp examinations were conducted, and corneal scraping was performed for Gram-chromotrope staining and polymerase chain reaction (PCR) analysis.
[Advances in clinical diagnosis and treatment of microsporidial keratitis].
Zhonghua Yan Ke Za Zhi
October 2024
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100730, China.
Article Synopsis
- Microsporidia, a type of unicellular microorganism, can infect the eyes and lead to a condition known as microsporidia keratitis (MK), which has two forms: microsporidian keratoconjunctivitis (MKC) and stromal keratitis (MSK).
- MKC generally improves on its own, but can escalate to MSK, a severe condition that risks vision and could cause corneal perforation.
- Despite its prevalence in Southeast Asia, especially during the rainy season, there's a lack of detailed case reports and understanding of MK in China, resulting in challenges with diagnosis and treatment, which this review aims to address.
Successful Treatment of Microsporidial Keratoconjunctivitis (MKC) With a Combination of Topical Voriconazole 1% and Gatifloxacin 0.5%: A Large Case Series of 29 Patients.
Cureus
November 2023
Medical Microbiology, All India Institute of Medical Sciences (AIIMS), Mangalagiri, IND.
Objective: This study aims to report the successful treatment of microsporidial keratoconjunctivitis (MKC) with the combination of topical drops of voriconazole (1%) and gatifloxacin (0.5%) in all 29 patients. Demography, clinical profile, and previous treatment history were also analyzed.
View Article and Find Full Text PDFMicrosporidial keratoconjunctivitis - first outbreak in Japan.
BMC Infect Dis
November 2023
Department of Parasitology, The National Institute of Infectious Diseases, Tokyo, Japan.
Background: Most cases of microsporidial keratoconjunctivitis are found in the Southern hemisphere. Our purpose was to investigate the first outbreak of microsporidial keratoconjunctivitis in Japan among healthy, immunocompetent soccer players from the same team during a 1-month period.
Case Presentation: This study is an observational case series.
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