Introduction: This is a single, level 1 trauma centre, prospective consecutive patient series with intramedullary infection in the presence of unstable tibial fracture treated using the Kirschner wire-reinforced, antibiotic cement nail.
Patients And Methods: A total of 10 consecutive patients (eight males and two females) with a mean age of 42 years (range, 20-59) suffering from infection after intramedullary nailing for tibial fracture, admitted during a period of 4 years, were included. An antibiotic cement-coated nail, handmade at the time of surgery, was implanted in all patients. This was followed by a standardised 6-week treatment protocol, extraction of the nail and definitive fixation.
Results: At 6 years of follow-up, infection eradication and bony union were possible in all of the patients. No further infection treatment was necessary; however, all of our patients underwent additional procedures (mean: four additional procedures per patient) for cosmetic or other non-infectious reasons (bone grafting, muscle flaps, etc.).
Conclusions: The antibiotic cement-coated nail seems to be an effective treatment for intramedullary infections of the fractured tibia.
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http://dx.doi.org/10.1016/j.injury.2013.05.001 | DOI Listing |
Arch Bone Jt Surg
January 2024
Department of Medical Physics and Radiology, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
This study aimed to evaluate the efficacy of antibiotic-loaded cement articulating spacers produced through a silicone mold in the two-stage revision of infected total knee arthroplasty. Five individuals were prospectively treated with 2-stage revision using spacers made by this mold. Clinical assessment was conducted during and after implantation using the WOMAC Score, Oxford knee score, and range of motion (ROM).
View Article and Find Full Text PDFFront Cell Infect Microbiol
January 2025
Department of Orthopedics, Fuyang City People's Hospital, Fuyang, China.
Objective: The purpose of this study was to investigate the clinical efficacy of antibiotic-loaded bone cement (ALBC) combined with Negative pressure wound therapy (NPWT) aspiration technique in the treatment of multidrug-resistant diabetic foot ulcers (MDRO-DFUs).
Methods: A retrospective analysis of the clinical data of 80 patients with MDROs-DFU who were used Vacuum sealing drainage (VSD) as NPWT excipient and met the inclusion criteria from January 2019 to January 2024 at our hospital. Patients were divided into an experimental group and a control group, with 40 cases in each.
J Clin Orthop Trauma
February 2025
Instituto de Ortopedia y Trauma Dr. Jaime Slullitel, San LUIS 2534 2000, Rosario, Santa Fe, Argentina.
Introduction: In the scenario of chronic osteomyelitis following an ankle fracture, limb salvage and ideally infection eradication, can be an alternative to amputation.Tibiotalocalcaneal arthrodesis is perhaps the most popular procedure. When performing fusion in osteomyelitis patients, external fixation is more commonly used, although there is some experience with internal fixation.
View Article and Find Full Text PDFBMC Musculoskelet Disord
January 2025
Institute of Statistics, National Yang Ming Chiao Tung University, 1001 University Road, Hsinchu City, 300, Taiwan.
Background: The standard treatment for periprosthetic joint infections (PJI) typically involves a two-stage resection arthroplasty using antibiotic-loaded bone cement (ALBC) spacers. This study hypothesizes that there is no significant correlation between antibiotic levels in blood and synovial fluid and the patient's kidney function, and that the success rates of staged resection arthroplasty are comparable between groups, specifically targeting gram-positive bacterial infections.
Methods: This retrospective review included patients treated from 2017 to 2022 with two-stage arthroplasty using vancomycin-loaded ALBC spacers, selectively targeting gram-positive infections.
Background: Kyphoplasty (KP) is a well-established procedure with a low complication risk, however, the procedure's safety in patients with comorbidities and in the setting of systemic infection remains uncertain with no clear guidelines. We present a unique case of KP in the setting of recurrent septicemia, which required subsequent salvage vertebrectomy.
Case Description: We present a clinical case of a 59-year-old diabetic male patient with a recent foot ulcer, positive for and .
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