Automatic seizure detection is significant for long-term monitoring of epilepsy, as well as for diagnostics and rehabilitation, and can decrease the duration of work required when inspecting the EEG signals. In this study we propose a novel method for feature extraction and pattern recognition of ictal EEG, based upon empirical mode decomposition (EMD) and support vector machine (SVM). First the EEG signal is decomposed into Intrinsic Mode Functions (IMFs) using EMD, and then the coefficient of variation and fluctuation index of IMFs are extracted as features. SVM is then used as the classifier for recognition of ictal EEG. The experimental results show that this algorithm can achieve the sensitivity of 97.00% and specificity of 96.25% for interictal and ictal EEGs, and the sensitivity of 98.00% and specificity of 99.40% for normal and ictal EEGs on Bonn data sets. Besides, the experiment with interictal and ictal EEGs from Qilu Hospital dataset also yields a satisfactory sensitivity of 98.05% and specificity of 100%.
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http://dx.doi.org/10.1016/j.compbiomed.2013.04.002 | DOI Listing |
PLoS One
January 2025
Instituto de Microelectrónica de Sevilla (IMSE-CNM), Consejo Superior de Investigaciones Científicas (CSIC) and Universidad de Sevilla, Sevilla, Spain.
Epilepsy is a prevalent neurological disorder that affects approximately 1% of the global population. Approximately 30-40% of patients respond poorly to antiepileptic medications, leading to a significant negative impact on their quality of life. Closed-loop deep brain stimulation (DBS) is a promising treatment for individuals who do not respond to medical therapy.
View Article and Find Full Text PDFBMC Med Inform Decis Mak
January 2025
The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China.
Background: The diagnosis and treatment of epilepsy continue to face numerous challenges, highlighting the urgent need for the development of rapid, accurate, and non-invasive methods for seizure detection. In recent years, advancements in the analysis of electroencephalogram (EEG) signals have garnered widespread attention, particularly in the area of seizure recognition.
Methods: A novel hybrid deep learning approach that combines feature fusion for efficient seizure detection is proposed in this study.
Epilepsy Behav
December 2024
Mayo Clinic, Department of Neurology, Divisions of Epilepsy and Child and Adolescent Neurology, 200 First Street SW, Rochester, MN 55905, United States.
Mov Disord Clin Pract
December 2024
Service de Neuropédiatrie, CHU Montpellier, Montpellier, France.
Epilepsy Behav
December 2024
Núcleo de Neurociências, Departamento de Fisiologia e Biofísica, Instituto de Ciências Biológicas - Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Centro de Tecnologia e Pesquisa em Magneto Ressonância, Programa de Pós-Graduação em Engenharia Elétrica, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. Electronic address:
This study used intra-hippocampal injections of Kainic Acid (KA) in Wistar rats to induce spontaneous recurrent seizures (SRS) after a 9-day latent period. A post-conditioning protocol with LPS, injected at the same site 72 h after the initial KA insult, was employed to trigger secondary competing processes. To evaluate the post-conditioning effect of LPS, 25 animals were divided into four groups: SAL-SAL (n = 6), KA-SAL (n = 6), SAL-LPS (n = 7), and KA-LPS (n = 6).
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